11-12-2023, 06:49 PM
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11-12-2023, 07:55 PM
(11-12-2023, 02:50 PM)HelloDiDi Wrote: [ -> ]I think you have a good chance on developing more underboob area as more side branching and fullness shows up, the very same that you've had going on for a while now.I am happy to read about your experiences on MG. What I recall is a tremendous sense of well being in addition to a widening in the pelvic area. You are quite an inspiration!
Ugh yea, it takes time. And "trust the process" isn't a lie, its absolutely true. Its a good place to be, far enough to know how this works. I'm confident it'll keep on giving as its been a stable climb for about three years now and I have never even truly stalled. Its like a tidal wave which comes up higher each time.
Swanson multi glandular has 150mg of BO and uterine each, also heart, liver and kidney tissue, 50mg of each. I would rather have this as nothing but uterine, but they don't sell it on its own. What the rest of the things do, I'm really not sure, but I'm feeling over all much better while I'm on it, similar to how ti was on Raw Fem back when it was available.
As I don't know the exact effect, I can only talk about how its making me feel and what body changes I'm noticing. I think my butt, hips and thighs have gotten thicker lately and there's that distinctive lower back pain that happens when pelvic tilt changes. I've felt all that familiar stuff from before come back during last two weeks. Its still early to tell but if this is what I think it is, it'll show up in full body pictures sooner rather than later. And breast development is self explanatory when you look at the pics I posted today. I've been experiencing the most intense growth pains I've had, likely even more intense than when I first started and that's quite amazing.
My mood has been mostly quite stable and its easier to stay on positive state of mind and I feel more balanced. I had the same effect previously when I did ovary + uterine + pituitary as a combination so I guess it was to be expected. But now with dosages and combination of NBE being different, it seems that I might get much better breast development from this. So far its been a really positive experiment and only for fifteen days and there's already a visible difference in pictures and how my clothes fit. Everything else I've kept closely as its been for some months now so I blame the glandular therapy for the changes.
12-12-2023, 07:32 AM
Lara, to coin a new phrase (when/where they talk about being a DHT mutant) at reddit I ask (or determine for myself) you that you must be a NBE/Hrt mutant and I'll explain.
Meaning, I think it's remarkable how your body responds to the hormonal shift using NBE/Hrt methods… all the changes, e.g. feminization of lipolysis is this theory of how the feminization of fat (and how quickly you respond) convinces me that theory is sound. When we started working together you followed my program nearly to the T, I designed that nbe program to not just maximize breast growth but also the feminization aspect too. I spent hours jumping down new rabbit holes (of scientific research that only a few scientists talked about). Trying to chase down this theory of how one can take our fat tissue by way of lipolysis and change its direction to female wasn't easy. What I found is not only is lipolysis feminizing but it also triggers the activation SIRT1 protein. I know the next part is going to be complex, so bear with me.
For instance:
We found that SIRT1 promoted mitochondrial biogenesis and respiration in adipocytes and expression of molecules like leptin, adiponectin, matrix metalloproteinases, lipocalin 2, and thyroid responsive protein was SIRT1-dependent. Independent validation of the proteomics dataset uncovered SIRT1-dependence of SREBF1c and PPARα signaling in adipocytes.
https://www.nature.com/articles/s41598-021-87759-x
I'll wrap it up for now because it's late and I need to sleep. I think the time you spent following the NBE I developed primed your body… or more specifically how your adipose/adipocytes respond like a cisfemale does. In this process, SIRT1 protein expression stops (or slows) aging. Now, maybe you don't see the drastic changes as I do, but it's remarkable. I mean you get a belly pouch and it doesn't develop into visceral fat… you process it all as female (sic) patterned adipose, that includes hips, buttocks, thighs etc.
Don't be too hard on yourself about your face, you've only been doing this for a little over 3 yrs if I'm not mistaken vs 37 years of testosterone/dht flowing through your body. The biggest facial changes (for myself) occur when I take 200-300mg of P4 rectally. And that part took years for me. It's infinitely maddening to compare ourselves to others. I see how it affects you when others get a particular nice comment and you don't… that part of Lara I don't like to see (I'm sure some others feel the same to a certain degree). My take is for you to keep telling yourself you're moving forward. Like go stand in front of a full length and laugh, dance, blow a fart… (okay that part is lame), you get the point, just let loose those miserable mindset of hate, indecision and regret. The stress you put on yourself doesn't help with your end goals.
I'll have to explain more of what I've said in this post later
Once again though, your change is remarkable… cheetah print looks good on you.
Phew, I'm out.
and I'll explain.Meaning, I think it's remarkable how your body responds to the hormonal shift using NBE/Hrt methods… all the changes, e.g. feminization of lipolysis is this theory of how the feminization of fat (and how quickly you respond) convinces me that theory is sound. When we started working together you followed my program nearly to the T, I designed that nbe program to not just maximize breast growth but also the feminization aspect too. I spent hours jumping down new rabbit holes (of scientific research that only a few scientists talked about). Trying to chase down this theory of how one can take our fat tissue by way of lipolysis and change its direction to female wasn't easy. What I found is not only is lipolysis feminizing but it also triggers the activation SIRT1 protein. I know the next part is going to be complex, so bear with me.
For instance:
We found that SIRT1 promoted mitochondrial biogenesis and respiration in adipocytes and expression of molecules like leptin, adiponectin, matrix metalloproteinases, lipocalin 2, and thyroid responsive protein was SIRT1-dependent. Independent validation of the proteomics dataset uncovered SIRT1-dependence of SREBF1c and PPARα signaling in adipocytes.
https://www.nature.com/articles/s41598-021-87759-x
I'll wrap it up for now because it's late and I need to sleep. I think the time you spent following the NBE I developed primed your body… or more specifically how your adipose/adipocytes respond like a cisfemale does. In this process, SIRT1 protein expression stops (or slows) aging. Now, maybe you don't see the drastic changes as I do, but it's remarkable. I mean you get a belly pouch and it doesn't develop into visceral fat… you process it all as female (sic) patterned adipose, that includes hips, buttocks, thighs etc.
Don't be too hard on yourself about your face, you've only been doing this for a little over 3 yrs if I'm not mistaken vs 37 years of testosterone/dht flowing through your body. The biggest facial changes (for myself) occur when I take 200-300mg of P4 rectally. And that part took years for me. It's infinitely maddening to compare ourselves to others. I see how it affects you when others get a particular nice comment and you don't… that part of Lara I don't like to see (I'm sure some others feel the same to a certain degree). My take is for you to keep telling yourself you're moving forward. Like go stand in front of a full length and laugh, dance, blow a fart… (okay that part is lame), you get the point, just let loose those miserable mindset of hate, indecision and regret. The stress you put on yourself doesn't help with your end goals.
I'll have to explain more of what I've said in this post later
Once again though, your change is remarkable… cheetah print looks good on you.
Phew, I'm out.
(03-09-2022, 05:39 AM)Lotus Wrote: [ -> ]Effects of growth hormone on adipose tissue
growth hormone on adipose tissue.
Carrel AL1, Allen DB.
Author information
Abstract
Physiological effects of growth hormone (GH) extend beyond the stimulation of linear growth. These include important metabolic effects upon adipose tissue. GH affects both proliferation and differentiation of preadipocytes, although this varies between clonal cell lines and preadipocyte cultures. Both preadipocytes and mature adipocytes possess specific GH receptors. GH may mediate its actions via these receptors, but some effects are indirectly mediated through the GH-mediated secretion of insulin-like growth factor-I (IGF-I) within adipose tissue. GH promotes lipolysis via inhibition of lipoprotein lipase, which hydrolyzes triglycerides in the circulation to make them available for triglyceride accumulation in adipose tissue. GH also stimulates hormone sensitive lipase (HSL), the rate-limiting step for release of stored triglyceride in adipocytes (lipolysis). As GH becomes utilized for various "non-growth" concerns (see Figure 1), awareness of the metabolic effects on adipocytes is important to understand the clinical effects seen with GH therapy.
http://www.ncbi.nlm.nih.gov/pubmed/11086655
12-12-2023, 08:10 AM
I didn't expect you to drop by, that's a nice surprise. 
This is really interesting stuff you posted, its tapping right into what I've been wondering about because my body changes have been exceptionally good in such a short time. I've been wondering why it seems so many NBE stuffs have worked on me so well, especially the combination I've been doing since around spring/summer this year.
Lot of that early stuff which is known to work, I'm still on. MSM+D3+calcium, ginseng which appears to work really nicely once I ramped the dose up enough. GABA and L-tyrosine, generally everything that helps with HGH and growth factors appears to make my body changes go wild. (Pointing to the part you quoted about GH.)
I try to not be so harsh on myself, its really difficult though as there's so much I learned early in life and I'm awfully perfectionist and just too harsh, not giving credit when its due and of course being somewhat blind to my body changes. That's what I need others for as they're not blinded by my dysmorphia and see what I have going on. I feel like I have about six month delay with my perception lagging behind.
But a HRT/NBE mutant? Gosh, maybe I am? I mean its obvious how my changes are exceptionally fast and dramatic and the way weight gain seems to hit 100% female pattern, let alone breast growth and all.... And even face changes, it seems that it might be getting quicker, but that's in line with so many transwomen I've seen, face change is slow and subtle and often it seems most of the change comes after some time on HRT. And what's that about reversing aging? Because I do look younger than I did just few years back, skin quality is from another world these days.
This is really interesting stuff you posted, its tapping right into what I've been wondering about because my body changes have been exceptionally good in such a short time. I've been wondering why it seems so many NBE stuffs have worked on me so well, especially the combination I've been doing since around spring/summer this year.
Lot of that early stuff which is known to work, I'm still on. MSM+D3+calcium, ginseng which appears to work really nicely once I ramped the dose up enough. GABA and L-tyrosine, generally everything that helps with HGH and growth factors appears to make my body changes go wild. (Pointing to the part you quoted about GH.)
I try to not be so harsh on myself, its really difficult though as there's so much I learned early in life and I'm awfully perfectionist and just too harsh, not giving credit when its due and of course being somewhat blind to my body changes. That's what I need others for as they're not blinded by my dysmorphia and see what I have going on. I feel like I have about six month delay with my perception lagging behind.
But a HRT/NBE mutant? Gosh, maybe I am? I mean its obvious how my changes are exceptionally fast and dramatic and the way weight gain seems to hit 100% female pattern, let alone breast growth and all.... And even face changes, it seems that it might be getting quicker, but that's in line with so many transwomen I've seen, face change is slow and subtle and often it seems most of the change comes after some time on HRT. And what's that about reversing aging? Because I do look younger than I did just few years back, skin quality is from another world these days.
12-12-2023, 08:20 AM
(11-12-2023, 07:55 PM)krisblue2 Wrote: [ -> ]I am happy to read about your experiences on MG. What I recall is a tremendous sense of well being in addition to a widening in the pelvic area. You are quite an inspiration!
It seems that BO+Uterine+Pit combo is really good on helping weight gain, and that it lands on the right places.... My experience points to BO doing a whole lot to breast development, but this combination does way more, especially on lower body. Call me crazy, but both times I've been on it, very quickly I have started to get symptoms of pelvic tilt changing and hips widening... Its happening again. Lower back pain in the lowest few vertebrae, feeling like my spine "wants" to bend into a new posture when ever I sit or stand upright, lying on my back feeling weird. And after a while, when I measure my height, I have lost some.
Quite a coincidence to have this happen again now that I've been on it for two weeks.
12-12-2023, 08:24 AM
12-12-2023, 09:17 PM
(12-12-2023, 08:20 AM)HelloDiDi Wrote: [ -> ](11-12-2023, 07:55 PM)krisblue2 Wrote: [ -> ]I am happy to read about your experiences on MG. What I recall is a tremendous sense of well being in addition to a widening in the pelvic area. You are quite an inspiration!
It seems that BO+Uterine+Pit combo is really good on helping weight gain, and that it lands on the right places.... My experience points to BO doing a whole lot to breast development, but this combination does way more, especially on lower body. Call me crazy, but both times I've been on it, very quickly I have started to get symptoms of pelvic tilt changing and hips widening... Its happening again. Lower back pain in the lowest few vertebrae, feeling like my spine "wants" to bend into a new posture when ever I sit or stand upright, lying on my back feeling weird. And after a while, when I measure my height, I have lost some.
Quite a coincidence to have this happen again now that I've been on it for two weeks.
ah yes, the pelvic tilt! the widening hips. and, my butt feels like a pillow when I sit. I'm surprised that there isn't a section here about pelvic tilt. I hadn't really noticed or thought about it until a couple of years ago when a bodywork practitioner pointed it out. "You have a pelvic tilt," he said! then he had me walk around the room and said, "sway more." I didn't return to that person. the only other male bodyworker I've gone to remarked about my additional curves above my waist. He said, "we'll get rid of that!" I didn't return. Women are much more sensitive as bodyworkers (my experience) and seem to intuitively work to promote my body changes. Happy for that! All the best to you as the light returns. Thanks for your updates on MG. xo
13-12-2023, 10:30 AM
Lol, yea, talk about butt pillow. And the crazy jiggle while walking, poking it into walls and stuff.... Its funny.
Little update today about lactation etc., I'm grabbing the 24mm flange cups today, I've been doing lower than normal hours to let my nipples heal a bit and wait for the new cups. I think they will be more suitable for now, the 28mm flange is just wide enough to cause a lot of blisters at the moment. Its a bit annoying as growing enough to fit just perfectly will likely take quite a lot of time as the 4mm jump is rather big. So for now I know 24mm will be better fit, it will allow approx 3mm space to swell by width which is perfect, more than that will cause heck of a lot of blisters until I grow enough. Its peculiar how precise this development is, I've taken note each time I have switched to wider ones that it happens precisely in certain size and once I completely grow into it, then the sucktion gets really intense and there's no blisters.
Also I'm taking a break from alfalfa, moringa and blessed thistle. Some or more than one are causing me bloating really easily, otherwise its working fine but something is upsetting my stomach and I want to troubleshoot which herb does it. I'm heading out of town today to stay with my girlfirend for a week and do the surgery consultation so perfect timing to go on with a bit simplified program. I have already proven the combination to being effective, but luckily with prolactin herbs there is quite a lot of choice, so when I want to go in full blast, I will likely know better which ones to choose and just ramp up the dosages enough.
I'm really happy about the lactation experiment, doing it without pharma drugs is definitely doable, albeit expensive and takes a fuckton of pumping. I'm very curious about trying to do a combination of some herbs, pumping and low/moderate dose of domperidone at some point to see how much easier that would be.
For breast development, I don't need to push for making a lot of milk, but having elevated prolactin and just droplets seems to be enough as they're obviously active and functioning, the milk supply doesn't seem to correlate with brast growth which of course makes sense, but the prolactin route has been extremely effective! I've grown on volume and maturity a LOT during the last about four months. I think this is something to be aware of to who ever seems to benefit from high prolactin levels.
And the crazy jiggle while walking, poking it into walls and stuff.... Its funny. Little update today about lactation etc., I'm grabbing the 24mm flange cups today, I've been doing lower than normal hours to let my nipples heal a bit and wait for the new cups. I think they will be more suitable for now, the 28mm flange is just wide enough to cause a lot of blisters at the moment. Its a bit annoying as growing enough to fit just perfectly will likely take quite a lot of time as the 4mm jump is rather big. So for now I know 24mm will be better fit, it will allow approx 3mm space to swell by width which is perfect, more than that will cause heck of a lot of blisters until I grow enough. Its peculiar how precise this development is, I've taken note each time I have switched to wider ones that it happens precisely in certain size and once I completely grow into it, then the sucktion gets really intense and there's no blisters.
Also I'm taking a break from alfalfa, moringa and blessed thistle. Some or more than one are causing me bloating really easily, otherwise its working fine but something is upsetting my stomach and I want to troubleshoot which herb does it. I'm heading out of town today to stay with my girlfirend for a week and do the surgery consultation so perfect timing to go on with a bit simplified program. I have already proven the combination to being effective, but luckily with prolactin herbs there is quite a lot of choice, so when I want to go in full blast, I will likely know better which ones to choose and just ramp up the dosages enough.
I'm really happy about the lactation experiment, doing it without pharma drugs is definitely doable, albeit expensive and takes a fuckton of pumping. I'm very curious about trying to do a combination of some herbs, pumping and low/moderate dose of domperidone at some point to see how much easier that would be.
For breast development, I don't need to push for making a lot of milk, but having elevated prolactin and just droplets seems to be enough as they're obviously active and functioning, the milk supply doesn't seem to correlate with brast growth which of course makes sense, but the prolactin route has been extremely effective! I've grown on volume and maturity a LOT during the last about four months. I think this is something to be aware of to who ever seems to benefit from high prolactin levels.
13-12-2023, 11:50 PM
15-12-2023, 01:37 PM
I got an early Christmas present. This dress is obviously not low shelf stuff, feels so luxurious. I'm going to glimmer with the snow this winter. My girlfriend is just so amazing, totally spoiling me with things. This dress is gonna make jaws drop once I'm done with body contouring, its licking every curve and hiding nothing. Except that it hangs straight below boobs as they're quite big, if I had something below that kept it in place or attached the dress on my bra band, that could solve the issue. Modelling tricks.
![[Image: 15-12-23-1.jpg]](https://i.postimg.cc/cJH4TFZG/15-12-23-1.jpg)
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