08-03-2015, 04:22 PM
Lets gang up on Lotus, and give him a spanking. Second thought, he MIGHT consider that a reward??? LOL
(03-03-2015, 08:22 AM)Lananonymous Wrote:(03-03-2015, 02:41 AM)twinklepose Wrote:(02-03-2015, 07:13 AM)Lananonymous Wrote:(31-12-2013, 05:09 PM)MonikaT Wrote: I've had no luck finding white peony as a supplement. I can only seem to find teas, and I don't want to mess with teas.
You might also want to look into DIM. http://www.jbc.org/content/278/23/21136.full
Hi Monica,
I ordered off amazon, Iowa Select Herbs White Peony Extract
I hope this helps.
Thanks for this link. What do you all consider the best reishi to use?
Also, what doses for each? I'm on 2,000mg of PM per day. Budding the past few weeks, though nothing visible yet.
Swanson Red Reishi Extract was recommended somewhere.
I'm not an expert with doses. I started out with recommended label (a dropper to a dropper and a half) twice a day and am now at three times a day with both.
(10-03-2015, 03:13 AM)myboobs Wrote: Gggggrrrrrr !!! Lotus !!!!!! Will you stop talking like a professor in goobldigook. Language and instead plain english so idiots like can understand . At my age I don't want to tax my limited grey cells :p
(03-03-2015, 05:45 AM)Lotus Wrote: Remember these "on and off" switches?, part of this good news, the other part.....not so good.
----------------------
The good news....…
the reductase responsible for the conversion of estrone (a weak estrogen) to 17b-estradiol (a potent estrogen) is the estrogenic type 1 17b-HSD and is the `on' switch for the estrogen receptor (ER). The oxidase activities responsible for the reverse reaction and the inactivation of 17b-estradiol are the type 2 and type 4 17b-HSDs, and these function as the `off' switch for the ER.
Thus, the activity of these 17b-HSD isoforms may regulate the ligand occupancy of ERa and ERb and their trans- activation in estrogen target tissues (Wu et al., 1993; Andersson, 1995; Labrie et al., 1997; 2000).
Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action http://humupd.oxfordjournals.org/content...3.full.pdf
---------------------------------
The not so good news.....
Phytoestrogens inhibit human 17b-hydroxysteroid dehydrogenase type 5
http://www.brc.dcs.gla.ac.uk/~rb106x/pub...bition.pdf
(07-02-2015, 07:37 PM)Lotus Wrote: This is a bit over simplified but Hydroxysteroid Dehydrogenases (HSDs) act like a gate-keeper just before steroids (hormones) bind to receptors (synthesis). Furthermore, these "gate-keepers" can flip the switch (a light switch) on/off to allow passage to the cell receptors. So in essence, they can inhibit or promote hormone activity. Finding a new class of HSD's is the next step, Aldo-keto reductases (AKRs) can help us get there.
(10-03-2015, 04:50 AM)myboobs Wrote: So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?