[myboobs]

Lets gang up on Lotus, and give him a spanking. Second thought, he MIGHT consider that a reward??? LOL

Noooooo ! He will poke our eyes with his boobies

[The First Aria]

Noooooo ! He will poke our eyes with his boobies

Good point MB.

[ellacraig]

Lets gang up on Lotus, and give him a spanking. Second thought, he MIGHT consider that a reward??? LOL

Noooooo ! He will poke our eyes with his boobies

I guess I could think of worse ways to loose my eyesight???...

[twinklepose]

I've had no luck finding white peony as a supplement. I can only seem to find teas, and I don't want to mess with teas.

You might also want to look into DIM. http://www.jbc.org/content/278/23/21136.full

Hi Monica,

I ordered off amazon, Iowa Select Herbs White Peony Extract

I hope this helps.

Thanks for this link. What do you all consider the best reishi to use?

Also, what doses for each? I'm on 2,000mg of PM per day. Budding the past few weeks, though nothing visible yet.

Swanson Red Reishi Extract was recommended somewhere.

I'm not an expert with doses. I started out with recommended label (a dropper to a dropper and a half) twice a day and am now at three times a day with both.

Thanks so much! I shall get Googling! x

[myboobs]

Gggggrrrrrr !!! Lotus !!!!!! Will you stop talking like a professor in goobldigook. Language and instead plain english so idiots like can understand . At my age I don't want to tax my limited grey cells :p

[Lotus]

Gggggrrrrrr !!! Lotus !!!!!! Will you stop talking like a professor in goobldigook. Language and instead plain english so idiots like can understand . At my age I don't want to tax my limited grey cells :p

I thought I did below.....plain terms??, there enzymes, think how aromatase or 5 alpha reductase inhibitors works (which are enzymes). It's much like those processes but 17-beta HSD's act like light switches, that is either on or off. Body builders manipulate certain designer steroids to enhance their programs with HSD's (Hydroxysteroid dehydrogenases). Licorice root is one such example which affects cortisol (the stress hormone), 11β-HSD is (11 beta Hydroxysteroid dehydrogenase). Certain NBE herbs can affect these enzymes, which we are already doing by utilizing them to control or affect DHT and aromatase.

Remember these "on and off" switches?, part of this good news, the other part.....not so good.

----------------------

The good news....…


the reductase responsible for the conversion of estrone (a weak estrogen) to 17b-estradiol (a potent estrogen) is the estrogenic type 1 17b-HSD and is the `on' switch for the estrogen receptor (ER). The oxidase activities responsible for the reverse reaction and the inactivation of 17b-estradiol are the type 2 and type 4 17b-HSDs, and these function as the `off' switch for the ER.

Thus, the activity of these 17b-HSD isoforms may regulate the ligand occupancy of ERa and ERb and their trans- activation in estrogen target tissues (Wu et al., 1993; Andersson, 1995; Labrie et al., 1997; 2000).

Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action http://humupd.oxfordjournals.org/content...3.full.pdf


---------------------------------

The not so good news.....

Phytoestrogens inhibit human 17b-hydroxysteroid dehydrogenase type 5
http://www.brc.dcs.gla.ac.uk/~rb106x/pub...bition.pdf

This is a bit over simplified but Hydroxysteroid Dehydrogenases (HSDs) act like a gate-keeper just before steroids (hormones) bind to receptors (synthesis). Furthermore, these "gate-keepers" can flip the switch (a light switch) on/off to allow passage to the cell receptors. So in essence, they can inhibit or promote hormone activity. Finding a new class of HSD's is the next step, Aldo-keto reductases (AKRs) can help us get there.

[myboobs]

So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?

[Lotus]

So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?

Yeah you're on the right track, it's still gobblygoo to me too. Estrogens and androgens take pathways to get to those hormone receptors, and then they go through something like the stove top jiffy popcorn tins, (lol, you remember those things?). Well once those molecules in the receptors bind (activate) to the nucleus (DNA) growth can occur. It doesn't happen to every cell, some of the hormones languish around and get lazy and get peed out, (what?, you have better way to say it lol?, expelled?, take a pick).

Certain phytoestrogens can be more effective than others, just like how estradiol is more potent than estriol and estrone, or how DHT is the most potent androgen. Frankly there's quite a few ways to get breasts going, everybody is different as we know. Some people carry more breast growth genes than others, why that is isn't fully understood. But.....some offensive tools are just now coming into focus, at least in my opinion.

[spanky]

I wish the study discussed in this abstract were available. If it is I cannot find it.

http://ict.sagepub.com/content/2/2/120.short

[Lotus]

I wish the study discussed in this abstract were available. If it is I cannot find it.

http://ict.sagepub.com/content/2/2/120.short

This PDF is working:

Hops (Humulus lupulus) Inhibits Oxidative Estrogen Metabolism and Estrogen-Induced Malignant Transformation in Human Mammary Epithelial cells (MCF-10A)

http://cancerpreventionresearch.aacrjour...3.full.pdf

Long-term exposure to estrogen resulting from a combination of early onset of menstruation, nulliparity or delayed first child birth, short duration of breast feeding, late menopause, and use of hormone replacement therapy (HRT; refs. 1, 2) increases the risk of hormone-dependent cancers in women (3, 4). Two major mechanisms for estrogen carcinogenesis have been proposed which include estrogen induced cell proliferation in estrogen receptor (ER) positive cells (hormonal pathway) and the formation of reactive estrogen metabolites (chemical pathway, Fig. 1; ref. 5). Understanding these mechanisms can lead to strategies for prevention of estrogen-dependent cancers which can enhance the quality of life for women as well as significantly reduce the cost of health care.