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Anti-Androgens

From the first study,

Type 1, 2 , 4 , 5 (17beta HSD) are breast growth potentiators

5 can go either way.

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(03-03-2015, 02:41 AM)twinklepose Wrote:  
(02-03-2015, 07:13 AM)Lananonymous Wrote:  
(31-12-2013, 05:09 PM)MonikaT Wrote:  I've had no luck finding white peony as a supplement. I can only seem to find teas, and I don't want to mess with teas.

You might also want to look into DIM. http://www.jbc.org/content/278/23/21136.full

Hi Monica,

I ordered off amazon, Iowa Select Herbs White Peony Extract

I hope this helps.

Thanks for this link. What do you all consider the best reishi to use?

Also, what doses for each? I'm on 2,000mg of PM per day. Budding the past few weeks, though nothing visible yet.

Swanson Red Reishi Extract was recommended somewhere.

I'm not an expert with doses. I started out with recommended label (a dropper to a dropper and a half) twice a day and am now at three times a day with both.
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(03-03-2015, 08:22 AM)Lananonymous Wrote:  
(03-03-2015, 02:41 AM)twinklepose Wrote:  
(02-03-2015, 07:13 AM)Lananonymous Wrote:  
(31-12-2013, 05:09 PM)MonikaT Wrote:  I've had no luck finding white peony as a supplement. I can only seem to find teas, and I don't want to mess with teas.

You might also want to look into DIM. http://www.jbc.org/content/278/23/21136.full

Hi Monica,

I ordered off amazon, Iowa Select Herbs White Peony Extract

I hope this helps.

Thanks for this link. What do you all consider the best reishi to use?

Also, what doses for each? I'm on 2,000mg of PM per day. Budding the past few weeks, though nothing visible yet.

Swanson Red Reishi Extract was recommended somewhere.

I'm not an expert with doses. I started out with recommended label (a dropper to a dropper and a half) twice a day and am now at three times a day with both.

Thanks so much! I shall get Googling! x
Reply

Gggggrrrrrr !!! Lotus !!!!!! Will you stop talking like a professor in goobldigook. Language and instead plain english so idiots like can understand . At my age I don't want to tax my limited grey cells :p
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(10-03-2015, 03:13 AM)myboobs Wrote:  Gggggrrrrrr !!! Lotus !!!!!! Will you stop talking like a professor in goobldigook. Language and instead plain english so idiots like can understand . At my age I don't want to tax my limited grey cells :p

I thought I did below.....plain terms??, there enzymes, think how aromatase or 5 alpha reductase inhibitors works (which are enzymes). It's much like those processes but 17-beta HSD's act like light switches, that is either on or off. Body builders manipulate certain designer steroids to enhance their programs with HSD's (Hydroxysteroid dehydrogenases). Licorice root is one such example which affects cortisol (the stress hormone), 11β-HSD is (11 beta Hydroxysteroid dehydrogenase). Certain NBE herbs can affect these enzymes, which we are already doing by utilizing them to control or affect DHT and aromatase.

(03-03-2015, 05:45 AM)Lotus Wrote:  Remember these "on and off" switches?, part of this good news, the other part.....not so good.

----------------------

The good news....…


the reductase responsible for the conversion of estrone (a weak estrogen) to 17b-estradiol (a potent estrogen) is the estrogenic type 1 17b-HSD and is the `on' switch for the estrogen receptor (ER). The oxidase activities responsible for the reverse reaction and the inactivation of 17b-estradiol are the type 2 and type 4 17b-HSDs, and these function as the `off' switch for the ER.

Thus, the activity of these 17b-HSD isoforms may regulate the ligand occupancy of ERa and ERb and their trans- activation in estrogen target tissues (Wu et al., 1993; Andersson, 1995; Labrie et al., 1997; 2000).

Hydroxysteroid dehydrogenases and pre-receptor regulation of steroid hormone action http://humupd.oxfordjournals.org/content...3.full.pdf


---------------------------------

The not so good news.....

Phytoestrogens inhibit human 17b-hydroxysteroid dehydrogenase type 5
http://www.brc.dcs.gla.ac.uk/~rb106x/pub...bition.pdf


(07-02-2015, 07:37 PM)Lotus Wrote:  This is a bit over simplified but Hydroxysteroid Dehydrogenases (HSDs) act like a gate-keeper just before steroids (hormones) bind to receptors (synthesis). Furthermore, these "gate-keepers" can flip the switch (a light switch) on/off to allow passage to the cell receptors. So in essence, they can inhibit or promote hormone activity. Finding a new class of HSD's is the next step, Aldo-keto reductases (AKRs) can help us get there.

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So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?
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(10-03-2015, 04:50 AM)myboobs Wrote:  So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?

Yeah you're on the right track, it's still gobblygoo to me too. Estrogens and androgens take pathways to get to those hormone receptors, and then they go through something like the stove top jiffy popcorn tins, (lol, you remember those things?). Well once those molecules in the receptors bind (activate) to the nucleus (DNA) growth can occur. It doesn't happen to every cell, some of the hormones languish around and get lazy and get peed out, (what?, you have better way to say it lol?, expelled?, take a pick).

Certain phytoestrogens can be more effective than others, just like how estradiol is more potent than estriol and estrone, or how DHT is the most potent androgen. Frankly there's quite a few ways to get breasts going, everybody is different as we know. Some people carry more breast growth genes than others, why that is isn't fully understood. But.....some offensive tools are just now coming into focus, at least in my opinion. Rolleyes

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(10-03-2015, 05:12 AM)Lotus Wrote:  
(10-03-2015, 04:50 AM)myboobs Wrote:  So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?

Yeah you're on the right track, it's still gobblygoo to me too. Estrogens and androgens take pathways to get to those hormone receptors, and then they go through something like the stove top jiffy popcorn tins, (lol, you remember those things?). Well once those molecules in the receptors bind (activate) to the nucleus (DNA) growth can occur. It doesn't happen to every cell, some of the hormones languish around and get lazy and get peed out, (what?, you have better way to say it lol?, expelled?, take a pick).

Certain phytoestrogens can be more effective than others, just like how estradiol is more potent than estriol and estrone, or how DHT is the most potent androgen. Frankly there's quite a few ways to get breasts going, everybody is different as we know. Some people carry more breast growth genes than others, why that is isn't fully understood. But.....some offensive tools are just now coming into focus, at least in my opinion. Rolleyes

I seem to have lazy booby genes . After 2 yrs I m still AA Sad
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(11-03-2015, 01:42 AM)myboobs Wrote:  
(10-03-2015, 05:12 AM)Lotus Wrote:  
(10-03-2015, 04:50 AM)myboobs Wrote:  So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?

Yeah you're on the right track, it's still gobblygoo to me too. Estrogens and androgens take pathways to get to those hormone receptors, and then they go through something like the stove top jiffy popcorn tins, (lol, you remember those things?). Well once those molecules in the receptors bind (activate) to the nucleus (DNA) growth can occur. It doesn't happen to every cell, some of the hormones languish around and get lazy and get peed out, (what?, you have better way to say it lol?, expelled?, take a pick).

Certain phytoestrogens can be more effective than others, just like how estradiol is more potent than estriol and estrone, or how DHT is the most potent androgen. Frankly there's quite a few ways to get breasts going, everybody is different as we know. Some people carry more breast growth genes than others, why that is isn't fully understood. But.....some offensive tools are just now coming into focus, at least in my opinion. Rolleyes

I seem to have lazy booby genes . After 2 yrs I m still AA Sad

Their there MB, maybe they need a stern talking to Wink time to wake em' up if you know what I mean. Maybe that thai breast slapping technique might work?, j/k Rolleyes
Reply

(11-03-2015, 02:32 AM)Lotus Wrote:  
(11-03-2015, 01:42 AM)myboobs Wrote:  
(10-03-2015, 05:12 AM)Lotus Wrote:  
(10-03-2015, 04:50 AM)myboobs Wrote:  So basically to suppress testorone and promote elstogen / estradol , best choice liquorice , healthy ffats best choice walnuts , best protein peanuts . Or am I barking up wrong tree ?

Yeah you're on the right track, it's still gobblygoo to me too. Estrogens and androgens take pathways to get to those hormone receptors, and then they go through something like the stove top jiffy popcorn tins, (lol, you remember those things?). Well once those molecules in the receptors bind (activate) to the nucleus (DNA) growth can occur. It doesn't happen to every cell, some of the hormones languish around and get lazy and get peed out, (what?, you have better way to say it lol?, expelled?, take a pick).

Certain phytoestrogens can be more effective than others, just like how estradiol is more potent than estriol and estrone, or how DHT is the most potent androgen. Frankly there's quite a few ways to get breasts going, everybody is different as we know. Some people carry more breast growth genes than others, why that is isn't fully understood. But.....some offensive tools are just now coming into focus, at least in my opinion. Rolleyes

I seem to have lazy booby genes . After 2 yrs I m still AA Sad

Their there MB, maybe they need a stern talking to Wink time to wake em' up if you know what I mean. Maybe that thai breast slapping technique might work?, j/k Rolleyes

Pmsl Big Grin give them 50 shades of grey treatment Dodgy
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