[Drew]

Sounds like something I will definitely have to try.  So you partially dissolve them?

Good that I'm no longer sexually active or he would wonder why he is suddenly growing boobs " alt="" title="">

"So you partially dissolve them?"  No no no! I only did that a few months ago when I was experimenting with the time it took for them to dissolve. I poured water on them at different temperatures to see how they reacted. Softened and dissolved pretty quickly. Just put one in your mouth and you'll see how quick they start falling apart.

I suppose you can also buy yourself a reusable injection device, liquify the PM with a little water, and inject it into your anal cavity. Should be pretty easy, and perhaps even a better option. Just ensure that the little liquid remain in there for a hour or so. In my case I'm pretty loose and relaxed down there and its easy for me to insert 2 capsules with two fingers. Once again, I'm not trying to be gross. Just giving you some new info that I haven't seen on this forum before.

Bev

I decided to try this, am on Estrofem 2mg atm but still have left over PM capsules so decided 500mg twice a day can't hurt. Actually it did a bit, have never before tried to shove anything up my bum, well not by myself anyway, but seems I'm not very good at it. Suppose finger nails aren't helping.

But have also done a little reading up and got this.

 In addition, drug bioavailability is affected by the site of drug absorption within the rectal cavity. The superior rectal veins go via the liver whereas the inferior rectal veins bypass liver metabolism, thus correct positioning of the dosage form, at the lower rectum, is crucial.

So assuming that means only just inside the bum so may be trying to push them in too deep? My longest finger is 6cm.

I never got any tingling or anything at all so inserted an estrofem 2 hours ago to see what happens. Just feel foggy, queasy, have a headache and bum hurts a bit. But will keep trying with the rest of my left over PM now I know where to position the capsules