[Lotus]

The information from studies I've seen indicate finasteride at all dosages inhibit DHT, starting within the first 2 weeks, though long term consistent use will have more results. Published reports say fin was well tolerated.........everyone is different so beware it could impact your health (liver too) differently than those " well tolerated " individuals.

Ahh, so sounds like there's a good chance I would be fine healthwise, and it is a strong enough t-blocker by itself to pair with PM? I wouldn't need to take SP or reishi root or something in addition?

I was under the belief that Spiro blocked the most of T to DHT conversion. Fin, however blocked the DHT, at the actual receptors.

Other way around, Finasteride blocks the conversion of testosterone to the more potent DHT by 5a-reductase, type 2 to be exact. Spirolactone acts by competing with DHT at the receptor level, and also increases the metabolic clearance of testosterone.

Combination therapy (i.e. Fin & Spiro) has been shown more effective at treating hirsutism (unwanted male pattern hair growth in women) BPH, prostate cancer, etc. than single drug therapy. Meaning yes, I would take a dual inhibitor like dutaseride, or another combination to inhibit DHT, lots of alternative are available. Reishi (a certain kind) is said to be a dual inhibitor like dutas (inhibits type I & II 5 alpha reductase). With something like PM adding Green Tea makes sense, and some fatty acids like GLA (gamma linoleic acid) could work too.