07-01-2015, 01:31 PM
I have had that twitching most of my life. I can tell you for certain that PM makes it worse in my case after more than 4 years on PM. I also very strongly suspect it to be responsible for my severe leg pain when driving for long hauls, and likely was either the cause or trigger for my mild high blood pressure and toe/ball of foot swelling and pain. The other major effect was the growth of boobies.
I think it sums up something like this: When you change something, things change.
I still take PM, but I never increase the dosage anymore, and I take regular breaks from it to minimize the assorted pains and twitching. My biggest concern about it these days is suspicion that it may have negative circulatory system effects over the long term. I worry some about the possible cardiovascular effects and how similar they might be to the cardiovascular effects I have heard about related to HRT.
I think it sums up something like this: When you change something, things change.
I still take PM, but I never increase the dosage anymore, and I take regular breaks from it to minimize the assorted pains and twitching. My biggest concern about it these days is suspicion that it may have negative circulatory system effects over the long term. I worry some about the possible cardiovascular effects and how similar they might be to the cardiovascular effects I have heard about related to HRT.

