[υαlεƦιε]

You also have to take into consideration the genetics of the person taking the medication. I am by no means an expert on the topic, however I can speak from experience that for me 500mg of good quality pm was enough to start feminising features of my body. I am sure a lot of others have had results from PM alone. When I took 50mcg of hrt in the form of estradiol patches the results were similar to the 500mg of pm. I am speculating here but it could be possible that some of us are more sensitive to hormonal changes or already have a lower t level and higher e naturally in our bodies.