05-12-2022, 04:38 AM
Hi Jennifer, because of your recent weight loss I'd start at 100mg (and I'll explain). This is something ben may not realize is that when older males lose weight their SHBG (sex hormone binding globulin) levels will go up, sending your estradiol levels down. This science on this is controversial as older science has SHBG being an estradiol amplifier and newer science saying it lowers estradiol (especially free E2 levels)
Synthesis and regulation of sex hormone-binding globulin in obesity
https://pubmed.ncbi.nlm.nih.gov/10997612/
Diet and sex hormone-binding globulin
https://pubmed.ncbi.nlm.nih.gov/10634401
In any event, talk to you doctor about losing weight and how it's affecting your estradiol and about adding the DIM.
I'd also recommend you get more protein in your diet (like that nice meal you shared the other day) especially when losing weight considering bone density loss, and as we age we are losing protein every year.
Good luck
Synthesis and regulation of sex hormone-binding globulin in obesity
https://pubmed.ncbi.nlm.nih.gov/10997612/
Diet and sex hormone-binding globulin
https://pubmed.ncbi.nlm.nih.gov/10634401
In any event, talk to you doctor about losing weight and how it's affecting your estradiol and about adding the DIM.
I'd also recommend you get more protein in your diet (like that nice meal you shared the other day) especially when losing weight considering bone density loss, and as we age we are losing protein every year.
Good luck