(20-05-2022, 12:57 AM)Lotus Wrote:(06-05-2022, 02:38 PM)HandofFate Wrote:I still have not had any growth. I am trying to lose all the weight I gained because it went to my stomach not my chest.
I am struggling with hunger so I take glucomannan every day. I tried using progesterone compounded cream on my chest and inner thighs. It did make them feel fuller, however the bust size never increased. I have been an A cup for years. No matter what I try.
I am currently taking berberine and fenugreek saponins hoping It will do something.
My recent blood test showed my hormone levels are great, yet I had no growth.
Hi HandofFate,
Fwiw, If the lab tests are accurate and within reference range for mtf's i believe the issue points to some obvious factors. Meaning hrt blood samples taken reflect what's in blood circulation, which indicates (to me) what you're taking isn't the issue, it's your metabolism of hrt meds. Or more to the point what's active in your target tissues…e.g breasts, testes, brain, hypothalamus/pituitary, adipose (fat) tissue, etc. It's not like we can take tissue samples of your breasts to see what hormones are present or deficient.
So, I see a few explanations:
Here I would recommend what to do, however, I want to help you figure out a game plan and for that I need your help.
- You have an extremely fast metabolism. Once estrogen diffuses into the cytoplasm and eventually reaches protein expression it can take seconds to minutes for estrogen receptors for DNA to reproduce, in other words what we want to achieve in new breast growth. The above is a crude explanation but essentially you could be excreting most of the supplemental (oral) estradiol out of your body way to fast. For estrogen synthesis there's four non-genomic pathways to which estrogen can synthesize. I've highlighted (in this thread) what I think is the most effective pathway for estrogen receptors. I tie in certain herbals that stimulate these pathways and for the most part people have had some success. Lol, I'm getting off track.
- There's a defective gene in your estrogen receptors that prevents maximum gene expression for breast growth.
- Your current plan is shuttling and storing too much estrogen to the tummy, thighs, ass and hips, this would be great if the results matched with new breast growth. The tummy holds on to diet resistant fat, aka visceral fat. Evidently there's more dht stored in visceral fat, but the more estradiol one takes it continues to supply stored fat to all the wrong places, unless you take control of it.
Take your time and analyze the above three scenarios of information and come up with a game plan on how'd you tackle it, then I'll give my thoughts of a new proposal too. In fact I will use this approach with anyone requiring help, in this way we can have a mutual agreement on which direction to take. Or you can ignore my take on things completely, I'm okay either way. " alt="" title="">
Regards, L.
I've seen people get several cupsizes without gaining weight so I think it does have to do with estrogen metabolism. Even gaining weight I don't get any growth.
Would being very obese like some members here help slow estrogen metabolism?