19-05-2016, 12:31 AM
Let's say BO does what it's advertised, hopefully it would work in tandem with PC, as the study below points out. I think the triglycerides both in PC and BO produce lipase activity, which catalyzes the hydrolysis of fats.
Studies in adipose tissue showed that treatment with ethynyl estradiol and progesterone, separately or in combination, increased lipoprotein lipase activity to a comparable extent. After treatment with progesterone alone, the increase was observed in the absence of elevated levels of triglycerides in blood. Triacylglycerol lipase activity assayed at pH 7.4 (hormone- sensitive lipase) was not affected by ethynyl estradiol or progesterone alone, but a significant decrease was observed under a combined regimen. None of these hormonal treatments modified the level of monoester lipase activity.
Taken together, the results point to major hormonal influences on lipid metabolism in liver and adipose tissue. However, it cannot be assessed whether these effects are due to the direct action of ethynyl estradiol and progesterone on liver and adipose tissue lipases and/or to some other altered metabolic response (s) secondary to the intake of the steroids.
- See more at: http://press.endocrine.org/doi/abs/10.12...QzX1p.dpuf
Studies in adipose tissue showed that treatment with ethynyl estradiol and progesterone, separately or in combination, increased lipoprotein lipase activity to a comparable extent. After treatment with progesterone alone, the increase was observed in the absence of elevated levels of triglycerides in blood. Triacylglycerol lipase activity assayed at pH 7.4 (hormone- sensitive lipase) was not affected by ethynyl estradiol or progesterone alone, but a significant decrease was observed under a combined regimen. None of these hormonal treatments modified the level of monoester lipase activity.
Taken together, the results point to major hormonal influences on lipid metabolism in liver and adipose tissue. However, it cannot be assessed whether these effects are due to the direct action of ethynyl estradiol and progesterone on liver and adipose tissue lipases and/or to some other altered metabolic response (s) secondary to the intake of the steroids.
- See more at: http://press.endocrine.org/doi/abs/10.12...QzX1p.dpuf
, as we know E2 is stored in aromatase and in SHBG (sex hormone binding globulin). 
cause there will blood ((haha)), pain, self doubt & torture (true), and perhaps lack of proper guidance, but nothing more than a few visits (3-4 different shrinks actually) would cure huh?. Oh wait!, then there was the visit to the endo (jerk) who discouraged my path, which I think led to a dark period (1.5 yrs actually) ultimately that led me to my current doc (finally, a trans friendly Physician). Btw, the endo suggested I remove the breat tissue 
, that's after he said " yep, those are real female breasts. At the time my GID was heavy gender fluid, and when I mention it to him (the gender fluid) he became very annoyed at the mere mention of it, his quote " there's no such things, I don't believe in the gender variants, it's either your full transition or nothing ".........so I thought to myself ( " oh hell no, you mf'er " you just discriminated against me). 
And although some part of me told me to take his shitty advice it pushed me to a dark place that ended up going to DIY hormones, dangerous times indeed. As for the endo, I got a nice letter announcing his retirement shortly after. I wonder how many TG folks got his shitty care?. 
(psa out).