13-01-2016, 11:23 PM
(13-01-2016, 10:33 PM)Tanya Marie Squirrel Wrote: Would lemon extract work? The kind that you use for flavoring? It is not synthetic, its pure lemon oil. I would assume that also needs diluting in water.
Good question, could be possible. I do like myboobs recipe with the Himalayan salt.
Btw, I think I discovered something interesting about MSM and the way it's metabolized. Meaning it's metabolized as part of the P450 cytochrome family, it looks similar to the way spiro, or ketoconazole is metabolized thru the inhibition of CYP17 enzyme (what is inhibiting DHT), and (this is the biggie) and a possible side clevage to C19 (aka-aromatase). This is not any current radar, but I'm pretty confident in saying that MSM inhibits DHT, and a pro-aromatase. But it also upregulates growth hormone,
Quote: MSM increases the expression of GH-related proteins including IGF-1R, p-IGF-1R, STAT5b, p-STAT5b, and Jak2 in osteoblastic cells and MSCs.I know right?,
Remember linoleic acid?, well, it also inhibits DHT too. As in EPO, vitex, walnuts etc.
linoleic acid autoxidation with 5 or 6 membered nitrogen-containing heterocycles inhibits CYP3A4
To understand the heterocycles visit here:
Heterocyclic Compounds
http://www2.chemistry.msu.edu/faculty/re...terocy.htm
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. Caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide.