20-01-2015, 06:29 PM
Ah, no worries. it took me a while to realize that estrogens and androgens compete inside the same receptor cell (called the cytoplasm). Even more confusing is that sometimes an androgen will bind to its receptor but not get activated, scientist are unsure why.
But the affinity is towards estradiol, for the most part these hormones must be in the free form for synthesis (you remember the 2% that gets delivered from SHBG/albumin).
And new research has determined there's a few more androgens, although I won't confuse you with them just yet lol.
But the affinity is towards estradiol, for the most part these hormones must be in the free form for synthesis (you remember the 2% that gets delivered from SHBG/albumin).
And new research has determined there's a few more androgens, although I won't confuse you with them just yet lol.