07-09-2014, 10:56 PM
(07-09-2014, 09:05 PM)Lotus Wrote: The lock and key procedure shows the binding process of drugs entering receptors cells.
A target cell may have between 2,000 and 100,000 receptors for a particular hormone.
Receptors, like other cellular proteins, are constantly being synthesized and broken down. Here's an important (pro active) step:
CYCLE YOUR NBE PROGRAMS WITH BREAKS!
Tolerance occurs when the person no longer responds to the drug in the way that person initially responded. Stated another way, it takes a higher dose of the drug to achieve the same level of response achieved initially.
Some drugs require a period of abstinence periodically to allow the cell to return to normal receptor density.