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Project X (hrt)

(25-05-2014, 01:41 PM)Larana Wrote:  Wow.Lotus.Thank you,you can help me very much.You have better and better idea.androgen blocker/estrogenic too this is great!

What is that aromatase?


There's an enzyme in the bodies of both men and women called aromatase. Its primary action is to produce female sex hormones, or estrogens. It produces them from male sex hormones (androgens) such as testosterone and their precursors.
Aromatase also converts androstenedione (a sex hormone precursor) to the female hormone estrone, another estrogen, although weaker than estradiol.
If you increase the activity of aromatase, you can increase levels of female sex hormones (estradiol, estrone).


What it means: blocks 5-ar?

5-ar - 5 alpha reductase - the enzyme that converts testosterone into dht. (It's like the aromatase enzyme). This is the one we want to prevent.

Inhibition of 5α-reductase results in decreased conversion of testosterone to DHT, leading to increased testosterone and estradiol. Other enzymes compensate to a degree for the absent conversion, spec voifically with local expression at the skin of reductive 17b-hydroxysteroid dehydrogenase, oxidative 3a-hydroxysteroid dehydrogenase, and 3b-hydroxysteroid dehydrogenase enzymes. Inhibition of the enzyme can be classified into two categories: steroidal, which are irreversible, and nonsteroidal. 5-α reductase 2 is the one we're interested in, there's more but it gets extremely complicated so I'll spare you the gory details.

Herbs that help block 5 ar, licorice, WP, Reishi, SP, pygeum, nettle root, BO (not an herb), Chinese Skullcap, progesterone cream is a strong 5 ar, linolenic acid, green tea.


5α-reductases catalyze the following chemical reaction:
a 3-oxo-5α-steroid + acceptor a 3-oxo-Δ4-steroid + reduced acceptor
http://wikipedia.org/wiki/5-alpha_reductase

is extract more effective than capsules?

Generally yes imo, the first pass of Metabolism is greatly reduced, (not eliminated) but releases directly into the bloodstream.


First pass metabolism is what occurs when a drug is absorbed from the GI tract. When a drug is taken orally it is absorbed into the portal circulation (the blood vessels of the liver). Many of these drugs are very efficiently metabolized (altered for elimination) as they pass through the portal circulation during this first time. It reduces the amount of active drug that gets into the general circulation. This is first-pass metabolism.

Well i have a little confusion. Angry
I take PM 1000 mg now,I'll be careful LC 250 mg /third days
And what is the white peony right dose with these together?

WP- 2-3x of the dropper mixed with water (6-8oz seems ok)

This is the rank: one day PM/another day LC and White Peony?

WP-I would say every other to start then combine (all) in the second week.


furthermore: does not Maca work against estrogenic?

It's said to balance the hormones, (helps control E-dominance)

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dear lotus do you know if peppermint works as good as spearmint ?..I only managed to get peppermint..turns out it tasted crazy amazing and I can't stuff drinking it <3 aw man you have to try dis stuff...anyway.....is this good for nbe ...I hear it is estrogenic so will it interfere with pm? (you know estro clash) ?_? is it an-andro thingy ?
can I keep drinking it cause I really love it =/


thanx
from the annoying rocket melon ;] from outer space! Big Grin
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you can use other mints. Cornmint has the same effect for lowering testosterone. but be careful of some mints' toxicity. Pennyroyal can be deadly with 1 tablespoon of extract. Other mints have way less of that harmful chemical. Peppermint and pennyroyal listed here http://www.nlm.nih.gov/medlineplus/drugi...All.html#P I'll leave it to Lotus to answer more.
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(26-05-2014, 12:37 AM)rocketmelon Wrote:  dear lotus do you know if peppermint works as good as spearmint ?..I only managed to get peppermint..turns out it tasted crazy amazing and I can't stuff drinking it <3 aw man you have to try dis stuff...anyway.....is this good for nbe ...I hear it is estrogenic so will it interfere with pm? (you know estro clash) ?_? is it an-andro thingy ?
can I keep drinking it cause I really love it =/


thanx
from the annoying rocket melon ;] from outer space! Big Grin

Hey there rocket,

Well, according to a 2007 (pay study) Peppermint has a stronger estrogenic activity, so we know that phytoestrogens exert there activity through ER-(estrogen receptors) mediated transactivation as the binding induces phytoestrogens ER's to act as ligand-dependent transcription factor.

Just remember that tea inhibits iron absorption:

Tea's Effect on Iron Absorption
http://caffeinatedepiphany.typepad.com/c...ption.html

So, imo (peppermint) activates receptors, and PM needs a metabolic activation to help it work better.
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(26-05-2014, 03:47 AM)Lotus Wrote:  
(26-05-2014, 12:37 AM)rocketmelon Wrote:  dear lotus do you know if peppermint works as good as spearmint ?..I only managed to get peppermint..turns out it tasted crazy amazing and I can't stuff drinking it <3 aw man you have to try dis stuff...anyway.....is this good for nbe ...I hear it is estrogenic so will it interfere with pm? (you know estro clash) ?_? is it an-andro thingy ?
can I keep drinking it cause I really love it =/


thanx
from the annoying rocket melon ;] from outer space! Big Grin

Hey there rocket,

Well, according to a 2007 (pay study) Peppermint has a stronger estrogenic activity, so we know that phytoestrogens exert there activity through ER-(estrogen receptors) mediated transactivation as the binding induces phytoestrogens ER's to act as ligand-dependent transcription factor.

Just remember that tea inhibits iron absorption:

Tea's Effect on Iron Absorption
http://caffeinatedepiphany.typepad.com/c...ption.html

So, imo (peppermint) activates receptors, and PM needs a metabolic activation to help it work better.

thank you lovely11 & lotus =]
and as lovely said it can be used an anti-androgen so it's fine without spearmint ...... lovely11 link showed peppermint is a lil cross bred plant...(des plants spearmint & water mint have being getting in on ;] ) so it's got the genes of spearmint which makes it a--OK right ?..and it's not as toxic as corn-mint so "yay" then (=

so you feel if peppermint activates receptors it's good to mix with pm?

and overall peppy peppermint is something I can take Big Grin as long as I watch muh iron levels... do you know foods good for promoting iron absorption or counteracting peppy mint's bad behavior ?

(= it's really a nice tasting tea ..I wonder if spearmint is this nice ...I take a whole lot not just for nbe but taste is great!

aw thnx everybody ;] lotus/lovely

-outerspace rocketed melon ;]
Reply

Mints are probably better for males who are doing nbe to take. I forgot to mention, mints increase LH and FSH which are given to cause multiple pregnancies. It might start menstruation sooner. it might extend it too. For women, one dose would be good to help the body go through menstruation.
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(26-05-2014, 04:17 PM)rocketmelon Wrote:  
(26-05-2014, 03:47 AM)Lotus Wrote:  
(26-05-2014, 12:37 AM)rocketmelon Wrote:  dear lotus do you know if peppermint works as good as spearmint ?..I only managed to get peppermint..turns out it tasted crazy amazing and I can't stuff drinking it <3 aw man you have to try dis stuff...anyway.....is this good for nbe ...I hear it is estrogenic so will it interfere with pm? (you know estro clash) ?_? is it an-andro thingy ?
can I keep drinking it cause I really love it =/


thanx
from the annoying rocket melon ;] from outer space! Big Grin

Hey there rocket,

Well, according to a 2007 (pay study) Peppermint has a stronger estrogenic activity, so we know that phytoestrogens exert there activity through ER-(estrogen receptors) mediated transactivation as the binding induces phytoestrogens ER's to act as ligand-dependent transcription factor.

Just remember that tea inhibits iron absorption:

Tea's Effect on Iron Absorption
http://caffeinatedepiphany.typepad.com/c...ption.html

So, imo (peppermint) activates receptors, and PM needs a metabolic activation to help it work better.

thank you lovely11 & lotus =]
and as lovely said it can be used an anti-androgen so it's fine without spearmint ...... lovely11 link showed peppermint is a lil cross bred plant...(des plants spearmint & water mint have being getting in on ;] ) so it's got the genes of spearmint which makes it a--OK right ?..and it's not as toxic as corn-mint so "yay" then (=

so you feel if peppermint activates receptors it's good to mix with pm?

and overall peppy peppermint is something I can take Big Grin as long as I watch muh iron levels... do you know foods good for promoting iron absorption or counteracting peppy mint's bad behavior ?

(= it's really a nice tasting tea ..I wonder if spearmint is this nice ...I take a whole lot not just for nbe but taste is great!

aw thnx everybody ;] lotus/lovely

-outerspace rocketed melon ;]

Oh yeah, you know I do space-nut, Wink

Check this one out,
http://fscn.cfans.umn.edu/prod/groups/cf...122645.pdf

Eating strawberries, green peppers, citrus fruits, leafy greens, seafood (proteins), grains, dried beans (legumes), foods rich in vitamin C can triple the bio-availability of iron.

However, I've found that some of these foods also inhibit iron absorption, so go figure right?. Wink

Eggs, peppermint, coffee, tea, cocoa , fiber, etc! Rolleyes

Oh yeah, spearmint and peppermint are from the same genus mentha family known as Lamiaceae.
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thanx ;]
good thing I eat meh veggies .
and I take a lot of vit C ..it's too easy
huh that's interesting in your link it says your body absorbs more iron when it's low ..that trust worthy machine always looking out for me =')

ee haha ;] thanx just the info I needed
have a nice day



Tongue writen by some kind of taking melon from space
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Lotus:

"WP-I would say every other to start then combine (all) in the second week. "

does it will good thing mixed these strong agents with PM?
you told me LC in every another day. Hmmm?
Let's see simple:

1500 mg PM (increased now)
450mg Licorice (every second day) or 250 mg?---->Once or twice?
3 drops White Peony every day----> for once or twice? 200 ml=7-8 oz about?
500mg Maca on every day,once-twice?

Thanks.How can you know so much things about it?Do you read it,or did you work in Pharmacy,are you a doctor? Big Grin

most of the time i don't understand biochemical operations, but the point is there Smile

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Red Reishi is on sale @Swansons: http://www.swansonvitamins.com/swanson-p...mg-60-caps

2 bottles with 60 capsules for $4.99 Smile
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