12-03-2015, 06:20 PM
(11-03-2015, 04:01 AM)myboobs Wrote:(11-03-2015, 03:11 AM)pom19 Wrote:(11-03-2015, 05:05 AM)iaboy Wrote: You are amazing Lotus. POM
That is why the nom de gure ------ boobologist
That's Master Boobologist to you MB. LOL
Thanks for the interpretation. That helps an old fart like me to understand all the little nuggets and tidbits you bring to the forum.
I really mean it.
Thanks , that means a lot. The invaluable research yielded some great finds in understanding what triggers breast growth. The mountains of scientific evidence imo suggest we don't need "proprietary blends" , spend big bucks on fancy gimmicks or subject our liver to near toxic levels, (e.g. in excess of 3,000 to 12,000 mg per supplement) to get there......
Research is difficult to interpret. Finding answers means changing search tactics, like "the bio-synthesis of", or "tissue promoters/expression" you catch my drift lol.
Recently I've been reading articles from a PhD of biology named Ray Peat, here's a few paragraphs from his articles.
Quote:polyunsaturated fats and prostaglandins stimulate the expression of aromatase, the enzyme that synthesizes estrogen, aspirin decreases the production of estrogen.
Quote: The amount of estrogen in tissue is decreased when progesterone is abundant. In the absence of progesterone, tissues retain estrogen even when there is little estrogen circulating in the blood.
Quote:Estrogen is produced in many tissues by the enzyme aromatase, even in the breast and endometrium, although these are considered "target tissues" rather than endocrine glands. Aromatase increases with aging.
Quote:Estrogen is inactivated, mainly in the liver and brain, by being made water soluble by the attachment of glucuronic acid and/or sulfuric acid.
-------------------------------------
http://raypeat.com/articles/articles/tis...ogen.shtml
(The highlighted text are NBE points of interest).
Estrogen's concentration in a particular tissue depends on many things, including its affinity or binding strength for components of that tissue, relative to its affinity for the blood; the activity in that tissue of the aromatase enzyme, which converts androgens to estrogen activity of glucuronidase enzyme, that converts water-soluble estrogen glucuronides into the oil soluble active forms of estrogen; and the sulfatases and several other enzymes that modify the activity and solubility of the estrogens. The "estrogen receptors," proteins which bind estrogens in cells, are inactivated by progesterone, and activated by many physical and chemical conditions.