28-06-2014, 05:58 AM
(28-06-2014, 05:49 AM)Lotus Wrote:(28-06-2014, 01:59 AM)spanky Wrote: Lotus -
So, if I understand correctly, it may be desirable to increase one's SHBG, if one wishes to have more feminine traits, or at least to increase one's relative level of estrogen. And if that is correct, how do you increase your SHBG levels, thus reducing testosterone levels in relation to estrogen? I take it that you would want to increase your aromatase.
In http://www.breastnexus.com/showthread.php?tid=19581, you indicated that soy protein isolate, sunflower oil, soybean oil, corn oil and alcohol can increase aromatase. Are there other sources?
spanky
Hi spanky,
This is from the mayo clinic,
Clinical Information
Sex hormone-binding globulin (SHBG), a homodimeric 90,000 to 100,000 molecular weight glycoprotein, is synthesized in the liver. Metabolic clearance of SHBG is biphasic, with a fast initial distribution from vascular compartment into extracellular space (half-life of a few hours), followed by a slower degradation phase (half-life of several days).
SHBG binds sex steroids with high affinity (KD approximately 10[-10]M), dihydrotestosterone (DHT) ->testosterone (T) ->estrone/estradiol (E). Although each monomeric subunit contains 1 steroid binding site, the dimer tends to bind only a single sex-steroid molecule. The main function of SHBG is sex-steroid transport within the blood stream and to extravascular target tissues. SHBG also plays a key role in regulating bioavailable sex-steroid concentrations through competition of sex steroids for available binding sites and fluctuations in SHBG concentrations. Because of the higher affinity of SHBG for DHT and T, compared to E, SHBG also has profound effects on the balance between bioavailable androgens and estrogens. Increased SHBG levels may be associated with symptoms and signs of hypogonadism in men, while decreased levels can result in androgenization in women.
http://www.mayomedicallaboratories.com/t...etive/9285
Estrogens, particularly in oral form, stimulate the hepatic production of sex hormone-binding globulin (SHBG) which binds with relatively high affinity to T, thereby reducing the bioavailability of androgens. The consequence of these dual effects is that both total and bioavailable testosterone levels are significantly reduced in women taking oral contraceptives or estrogen replacement for ovarian insufficiency.
As far Aromatase boosters go I read that tequila is one, it's also important to note that these are listed as AI's,
Aromatase Inhibitors
Foods that inhibit aromatase include blueberries, celery, sour cherries, cranberries, red grapes, purple grape juice, horseradish, kale, tomatoes, white button mushrooms and cruciferous vegetables such as broccoli, cabbage, cauliflower and Brussels sprouts. FoodForBreastCancer.com says these foods also enhance the effectiveness of aromatase inhibitors. If you have estrogen-dependent breast cancer, seek the advice of your oncologist before including these foods in your diet.