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AK_Presence   02-08-2025, 02:55 PM
#1
I Missed My Puffy Nipples — So I Built an 8-Week Hormone Protocol


Hey folks,

For my introduction to the site I wanted to share a personal experiment I’ve been driving for a while now. I’m a 19-year-old fit, muscular male (80kg), and this whole thing started when I casually tried 6mg Estova and 100mg Spiro for a week.

To my surprise, that short run gave me incredibly sensitive nipples, a surreal shift in my sense of smell, and a dreamy emotional softness that I honestly miss more than I expected. I stopped because I didn’t want things to go too far, but that experience has stayed with me — like my body briefly unlocked a mode I didn’t know I wanted.

Now I’m back with a more intentional plan. This time, no Spiro. I’m keeping testosterone active to preserve some grounding, libido, and masculinity. But I’m chasing something different: nipple pleasure, emotional immersion, and a soft sensual state that sits somewhere between genders — not necessarily moving away from who I am, but tuning into a side I’ve barely explored.


What This Is — and What It’s Not

This isn’t a full-on feminization HRT cycle. It’s not a transition (at least not for now). It’s a focused 8-week hormonal experiment to intentionally tap into prolactin-driven sensitivity, emotional rewiring, and sensual embodiment — without trying to permanently change my body.

If I start budding, I’ll try to pull back. But I’m also mentally prepared for the possibility that it might not fully reverse. If it sticks, I’ll just commit to it — and I already have a follow-up experiment in mind if that happens. Not ideal, but not something I’m afraid of either.


Protocol Overview

Estrofem: 4mg/day (2mg AM + 2mg PM), tapering to 2mg/day in Week 7 
Domperidone: Starting 10mg AM → 20mg/day by Week 3 (10mg AM/PM), tapering Week 7 
Progesterone (Utrogestan 100mg): Rectal 2x/week starting Week 3, building to 4x/week by Week 6 
Breast Pump: Daily, 15 minutes 

Week 7–8: Taper down to avoid long-term changes, hold sensitivity


Expected Effects by Week

Week 1–2 — Smell sensitivity, mood softening, early nipple tingles 
Week 3–4 — Erotic/emotional shift, swelling begins 
Week 5–6 — Deep sensual state, nipple fullness, dreamy response 
Week 7–8 — Controlled taper, maintain what worked, avoid glandular commitment


Hormonal Targets (Estimate)

Estradiol (E2): ~200–300 pmol/L → peaking ~600–900 pmol/L 
Prolactin: ~250 → peaking ~1200–1400 mIU/L 
Testosterone: Slightly suppressed but still active (~14–18 nmol/L)


Risks I'm Aware Of

– Breast tissue development — possible, especially Weeks 4–6 
– Galactorrhea — not a goal, but possible with domperidone 
– Mood instability — tracking and journaling it 
– Fertility impact — low concern for now


My Supplies

Estrofem 2mg — 112 tablets 
Utrogestan 100mg — 90 capsules 
Domperidone 10mg — 200 tablets 
Electric breast pump — daily stimulation



8-Week Protocol: Dosage & Expected Effects


Week 1 
– Estrofem: 4mg/day (2mg AM + 2mg PM) 
– Domperidone: 10mg AM 
– Progesterone: — 
– Notes: Nipple tingling, mood softening, smell shifts

Week 2 
– Estrofem: 4mg/day 
– Domperidone: 10mg AM 
– Progesterone: — 
– Notes: Emotional tone shift, early nipple focus

Week 3 
– Estrofem: 4mg/day 
– Domperidone: 10mg AM + 10mg PM 
– Progesterone: 2x/week (Mon/Fri, rectal) 
– Notes: Prolactin surge, dreamy state, light swelling

Week 4 
– Estrofem: 4mg/day 
– Domperidone: 20mg/day 
– Progesterone: 2x/week 
– Notes: Nipple bonding, skin softness, erotic onset

Week 5 
– Estrofem: 4mg/day 
– Domperidone: 20mg/day 
– Progesterone: 3x/week 
– Notes: Discharge possible, erotic peak, nipple fullness

Week 6 
– Estrofem: 4mg/day 
– Domperidone: 20mg/day 
– Progesterone: 4x/week 
– Notes: Sensual/erotic climax, deeply embodied

Week 7 
– Estrofem: 2mg/day 
– Domperidone: 10mg/day 
– Progesterone: 2x/week 
– Notes: Taper begins — hold sensitivity, reduce gland growth risk

Week 8 
– Estrofem: 2mg/day 
– Domperidone: 10mg/day 
– Progesterone: — 
– Notes: Exit or “climax” week — journal, observe, reflect



Weekly Updates Coming

I’ll be posting active WEEKLY UPDATES once I begin — tracking mood, physical changes, nipple response, erotic state, and anything unexpected. Journaling will be part of it. This is a lifestyle exploration, not a prescription for anyone else.


TL;DR

– 19 y/o male doing 8-week hormone experiment for sensation, not transition 
– Estrofem + Domperidone + Progesterone + breast stimulation 
– Keeping testosterone active (no anti-androgens) 
– Goal: nipple sensitivity, emotional immersion, dreaminess 
– Risk of budding acknowledged — will either taper or commit and shift into a second experiment 
– Weekly updates will follow once experiment begins



I know this kind of protocol sits in a grey area — not quite transition, not quite casual — so if you’ve experimented with anything similar, or have thoughts/feedback, I’m really open to hearing it.

If this sparks something in you — whether curiosity, advice, warnings, or encouragement — feel free to drop it here. Would love to talk with others thinking along the same lines.


- AK_Presence
Vana_B   04-08-2025, 02:59 PM
#2
(02-08-2025, 02:55 PM)AK_Presence Wrote: To my surprise, that short run gave me incredibly sensitive nipples, a surreal shift in my sense of smell, and a dreamy emotional softness that I honestly miss more than I expected. I stopped because I didn’t want things to go too far, but that experience has stayed with me — like my body briefly unlocked a mode I didn’t know I wanted.

I view it as turning on a 'cheat mode' in a video game.  I cycle on and off, typically in 3 month intervals and adjust dosages where my nipples feel plump, full, and highly erotic.  I do back off on the dosages if they get too tender / start budding.   If you really want to increase prolactin, get a breast milk pump and use it several times a day.   It s certainly something I miss and crave during my off months.   I don't supress my T, other than taking green tea and saw palmetto to help lower DHT.  I am mostly using a topical program of Bi-est and Progesterone.  I also use a home made PM infused lotion on most of my body daily.  

I never considered myself trans or have any type of gender dysphoria, but have learned how euphoric estrogen/PM/NBE can make me feel.   What truly amazes me is how fast the feeling comes back once I start back ( and dissipates once I stop ).  Up-regulation of estrogen receptors is at work here. 
   
Even with my on/off approach and stopping before I reach budding,  I still have noticeable breast growth (B cup) and big nipples that show through every shirt.   I also lift weights and bench hard, so carry alot of muscle on my chest making it look even bigger.  I also can gain weight like crazy during the 'on' part of the program, each time a bit more remains on my chest after I cut back on the weight.

Good luck with your experiments!
chus32   06-09-2025, 06:08 PM
#3
Hi @AK_Presence
I'm very curious about your experiment. Was the result as expected? 
I've ordered my first set of E (Estrofem) but I plan to make it last longer.
Thanks!!
BoyGrowingUp   19-09-2025, 07:19 AM
#4
Hi, I'm very interested in your regimen and would like to try it. How has this trip gone for you? Have you noticed any significant changes?

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