Quote:Only in male-to-female transsexuals in whom progestative chemical castration is combined with feminising estrogen therapy will full acini and lobular formation occur. Hence, combined progestative anti-androgens and estrogens is necessary for the genetically male breast to mimic the natural histology of the female breast.[
How important all of this is to optimal feminisation remains unclear and likely varies from individual to individual. What is clear is that Progestogens do play an important part in, among other things, proper breast development. Given that, and the lack of any compelling reason not to use them, it seems clear that a Progestogen should be a part of any optimal MTF HRT regimen.
(23-08-2016, 09:41 PM)Sofia Lauren Bunny Wrote: Ha ha, nice Lotus, I was going to point that section as well as it was one of the things that stood out to me. Unfortunately I was already starting to dose as I was posting the link. What I am curious is if progesterone is needed for development, which is better, ingestion via pills or applying topically via cream.
(24-08-2016, 12:40 AM)Lotus Wrote: Lol ok. Actually......I highlighted that part cause I know this study having covered it before, the histology of the study was very thorough. Topical application has better results versus oral, (which has shit bioavailability). Good find though, I like seeing urban legends displaced.
(24-08-2016, 12:40 AM)Lotus Wrote: Topical application has better results versus oral, (which has shit bioavailability). Good find though, I like seeing urban legends displaced.