Thanks for answering, but as I posted before, I will be talking to my doctor when I see him, just trying to get person experiences here. I believe thats what forums are for. Even though the bottles indicate once a day on each, I'm following that. The point of my question is, being on such a low dose, would it be more effective in a full dose one time a day or two low doses 12 hours apart. Again, I'm only asking this because it's a low dose. Otherwise there would be no question on what I can do. I have no problem following what my doctor says, but getting some research done before seeing him will help me ask the right questions as well.