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Breast Growing Notes

#21

REISHI


(09-08-2014, 12:13 AM)Lotus Wrote:  Estrogen-like activity of ethanol extract of Ganoderma lucidum
Abstract
The ethanol extract from the fruiting body of Ganoderma lucidum was tested for its estrogen-like activity by using the cell proliferation assay (MCF-7 cells, human breast cancer cells), as well as the estrogen receptor binding assay, and pS2 mRNA expression assay in MCF-7 cells in vitro and uterotrophic assay in vivo. The ethanol extract of G. lucidum showed signifi cant positive effects on the proliferation of MCF-7 cells. This proliferation effect is related to the estrogenic activity of G. lucidum, because this proliferation activity was inhibited by the addition of the antiestrogenic compound ICI 182,780. The ability to bind to human estrogen receptors (hERs) α and β of the ethanol extract of G. lucidum was confirmed by using the coactivator-bacterial alkaline phosphatase system. ER-dependent cell responsibilities were investigated by examining the regulation of gene transcription for pS2 in MCF-7 cells. Our results demonstrated that the pS2 mRNA levels are significantly increased by the ethanol extract of G. lucidumvia an estrogen-like manner. Additionally, young rats that received the ethanol extract of G. lucidum (200 mg/kg per day) for 3 days showed a signifi cant increase (growth approximately twofold compared with the control group) in uterine weight after each treatment, which supports the estrogen-like activity of the ethanol extract of G. lucidum in vivo. It was concluded that the ethanol extract of G. lucidum showed estrogen-like activity, which may be useful in regulating hormone levels to treat related diseases such as osteoporosis if safety is fully guaranteed.
http://link.springer.com/article/10.1007...008-0992-2

'A general Ganoderma lucidum extract does not separate the triterpenoids and the polysaccharides present in the mushroom, which make up the ethanolic and water-soluble extracts, respectively. The standard dose for the basic extract is 1.44g – 5.2g. The most popular dose is 5.2g, taken in three doses of 1,800mg.

The standard dosage for the ethanolic extract is 6mg.

The water-soluble extract should be dosed similarly to the basic extract.

'The basic extract is essentially dehydrated mushroom powder, which makes it about 10 times as potent as the actual mushroom. This means that 5g of extract is similar to about 50g of whole mushroom.'


Inhibition of 5α-reductase results in decreased conversion of testosterone to DHT, leading to increased testosterone and estradiol. Other enzymes compensate to a degree for the absent conversion, spec voifically with local expression at the skin of reductive 17b-hydroxysteroid dehydrogenase, oxidative 3a-hydroxysteroid dehydrogenase, and 3b-hydroxysteroid dehydrogenase enzymes. Inhibition of the enzyme can be classified into two categories: steroidal, which are irreversible, and nonsteroidal. 5-α reductase 2 is the one we're interested in,


Chapter 9Ganoderma lucidum (Lingzhi or Reishi)
http://www.ncbi.nlm.nih.gov/books/NBK92757/
A Medicinal Mushroom

Triterpene content ranged from undetectable to 7.8% and the polysaccharide content varied from 1.1–5.8% (Chang and Buswell 2008). Such variations can occur for several reasons, including differences in the species or strains of mushroom used and differences in production methods.

Anti-androgenic activities of Ganoderma lucidum.
http://www.ncbi.nlm.nih.gov/pubmed/16029938


An Update on Plant Derived Anti-Androgens
http://endometabol.com/?page=article&article_id=3644


The anti-androgen effect of ganoderol B isolated from the fruiting body of Ganoderma lucidum.
http://www.ncbi.nlm.nih.gov/pubmed/17499997


Recent advances in the chemistry and pharmacological activity of new steroidal antiandrogens and 5 alpha-reductase inhibitors.
http://www.ncbi.nlm.nih.gov/pubmed/15853706

http://examine.com/supplements/Ganoderma+lucidum/

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Messages In This Thread
Breast Growing Notes - by Lotus - 09-12-2014, 08:19 PM
RE: The Breast Growing Guide 101 - by Lotus - 06-10-2015, 05:03 PM
RE: The Breast Growing Guide 101 - by Lotus - 06-10-2015, 05:08 PM
RE: The Breast Growing Guide 101 - by Lotus - 06-10-2015, 05:26 PM
RE: The Breast Growing Guide 101 - by Huggy - 06-10-2015, 09:40 PM
RE: The Breast Growing Guide 101 - by xxd - 10-11-2015, 06:52 AM
RE: The Breast Growing Guide 101 - by xxd - 10-11-2015, 06:54 AM
RE: The Breast Growing Guide 101 - by BlueCoral - 14-09-2016, 09:50 PM
RE: The Breast Growing Guide 101 - by Lotus - 15-09-2016, 12:06 AM
RE: The Breast Growing Guide 101 - by BlueCoral - 16-09-2016, 03:15 AM
RE: The Breast Growing Guide 101 - by peekaboobs - 16-09-2016, 08:12 AM
RE: The Breast Growing Guide 101 - by Lotus - 17-09-2016, 02:30 AM
RE: The Breast Growing Guide 101 - by Lotus - 17-09-2016, 02:22 AM
RE: Breast growing notes - by Stevenator. - 22-10-2016, 05:35 PM
RE: breast growing notes - by BeautifulBambi - 24-12-2016, 04:34 AM
RE: breast growing notes - by bunnysdead - 12-03-2017, 05:53 PM
RE: breast growing notes - by BlueCoral - 17-03-2017, 10:02 PM
RE: breast growing notes - by Lotus - 19-03-2017, 03:01 AM
RE: breast growing notes - by BlueCoral - 22-03-2017, 10:17 PM
RE: breast growing notes - by shaneny - 07-04-2017, 12:58 AM
RE: breast growing notes - by Lotus - 11-04-2017, 07:13 AM
RE: breast growing notes - by Lotus - 11-04-2017, 07:05 AM
RE: breast growing notes - by Happyme - 21-04-2018, 01:25 PM
RE: breast growing notes - by BlueCoral - 26-06-2018, 01:18 AM
RE: breast growing notes - by Billie - 07-04-2017, 02:00 AM
RE: breast growing notes - by Lotus - 11-04-2017, 07:25 AM
RE: breast growing notes - by MeganJ - 11-04-2017, 06:34 PM
RE: breast growing notes - by Birgit - 11-04-2017, 05:29 PM
RE: breast growing notes - by ccoleman - 19-04-2017, 08:58 AM
RE: breast growing notes - by Midna - 20-03-2018, 09:26 AM
RE: breast growing notes - by mayabili - 21-04-2018, 07:42 AM
RE: breast growing notes - by kevin142001 - 20-05-2021, 09:57 AM
RE: breast growing notes - by Crystal Amethyst - 11-09-2022, 02:28 PM
RE: breast growing notes - by Lotus - 11-09-2022, 11:32 PM
RE: breast growing notes - by Crystal Amethyst - 12-09-2022, 12:57 AM
RE: breast growing notes - by Lotus - 14-10-2022, 01:55 AM
RE: breast growing notes - by Jennifer - 13-10-2022, 08:35 PM
RE: breast growing notes - by Lotus - 14-10-2022, 02:03 AM
RE: breast growing notes - by Jennifer - 15-10-2022, 09:34 PM
RE: breast growing notes - by Lotus - 16-10-2022, 05:21 AM
RE: breast growing notes - by Jennifer - 16-10-2022, 08:39 AM
RE: breast growing notes - by Jennifer - 30-10-2022, 07:59 PM
RE: breast growing notes - by Lotus - 02-11-2022, 03:58 AM
RE: breast growing notes - by Mel87 - 02-11-2022, 12:02 PM
RE: breast growing notes - by crg82 - 29-11-2022, 03:06 PM
RE: breast growing notes - by journey_tgb - 22-11-2023, 08:47 PM
RE: breast growing notes - by Sarah Cal - 19-12-2022, 12:06 AM
RE: Breast Growing Notes - by Lotus - 11-12-2023, 04:34 AM
RE: Breast Growing Notes - by Lotus - 30-12-2023, 06:22 AM
RE: Breast Growing Notes - by Jennifer - 30-12-2023, 10:31 AM
RE: Breast Growing Notes - by Lotus - 31-12-2023, 06:07 AM
RE: Breast Growing Notes - by Tania80 - 02-01-2024, 03:51 PM
RE: Breast Growing Notes - by notveryinteresting - 27-01-2024, 09:55 AM
Beth14 - by Beth14 - 28-01-2024, 12:43 AM
RE: Breast Growing Notes - by Toni68! - 06-02-2024, 08:09 PM
RE: Breast Growing Notes - by Tania80 - 13-02-2024, 01:15 PM
RE: FAQ-The Genetic Male NBE Guide - by Lotus - 10-12-2014, 01:06 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 01:19 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 01:27 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 01:31 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 01:39 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 01:42 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 01:46 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 02:04 AM
RE: FAQ NBE Guide - by Lotus - 10-12-2014, 02:26 AM
RE: FAQ-NBE Guide - by Lotus - 10-12-2014, 02:59 AM
RE: FAQ- NBE Guide - by Lotus - 14-12-2014, 12:36 AM
RE: FAQ-NBE Guide - by Lotus - 14-12-2014, 02:23 AM
RE: FAQ-NBE Guide - by Lotus - 14-12-2014, 02:43 AM
RE: FAQ- NBE Guide - by Lotus - 21-03-2015, 03:20 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 03:25 AM
RE: FAQ- NBE Guide - by Lotus - 21-03-2015, 03:28 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 03:31 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 03:35 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 03:37 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 03:59 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 04:05 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 04:07 AM
RE: FAQ-The Genetic Male NBE Guide - by Lotus - 21-03-2015, 04:29 AM
RE: FAQ-NBE Guide - by Lotus - 21-03-2015, 04:38 AM
RE: FAQ-NBE Guide - by Lotus - 27-04-2015, 11:31 PM
RE: FAQ-NBE Guide - by Lotus - 28-04-2015, 12:19 AM
RE: FAQ-NBE Guide - by Lotus - 29-04-2015, 05:21 PM
RE: FAQ-NBE Guide - by Lotus - 29-04-2015, 06:57 PM
RE: The Braest Growing Guide 101 - by Lotus - 06-10-2015, 04:28 PM



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