22-02-2013, 02:48 AM
Circeena,
I am currently taking tamulosin for BPH, together with SP (which is supposed to work well together with tamulosin) and PM (see my recent thread on PM & blood pressure for dosage details, although the BP effects Inoted were probably due to cholestyramine). I don't take finasteride; it has never struck me as one of the more effective prescription pharmaceuticals and even my urologist only very tentatively suggested it. SP may be almost as effective and has less side effects. I don't know of any actual interactions between PM and SP although many think that PM is best left to do its own thing. Both finasteride and SP are 5-aromatase inhibitors which help prevent the conversion of testosterone into DHT, but PM itself contains beta-sitosterol which itself is an 5-ARI. I also take some additional beta-sitosterol since it is a constituent of another supplement I take. Effects have been generally similar to those reported by PansyMae although my breast development is much less impressive. As for brain rewiring, the phytoestrogen in PM works by bonding to estrogen receptors in the body, including the brain as well as the breasts so there are likely to be brain effects as well as boob effects! What these will be will vary fom person to person.
Note that 5-ARIs will only inhibit conversion of T to DHT, but probably do little to inhibit T production. I was prescribed spironolactone over an 18 month period, which does inhibit T production and seems to have finished off what was left of my male function, apparently permanently. Subsequently stopping PM and taking Butea superba and later tongkat ali for several months did little or nothing to restore function. I have a suspicion that taking Siterone (ciproterone) as proposed by PattiJT might have a similar effect in the long term.
Hope this helps.
I am currently taking tamulosin for BPH, together with SP (which is supposed to work well together with tamulosin) and PM (see my recent thread on PM & blood pressure for dosage details, although the BP effects Inoted were probably due to cholestyramine). I don't take finasteride; it has never struck me as one of the more effective prescription pharmaceuticals and even my urologist only very tentatively suggested it. SP may be almost as effective and has less side effects. I don't know of any actual interactions between PM and SP although many think that PM is best left to do its own thing. Both finasteride and SP are 5-aromatase inhibitors which help prevent the conversion of testosterone into DHT, but PM itself contains beta-sitosterol which itself is an 5-ARI. I also take some additional beta-sitosterol since it is a constituent of another supplement I take. Effects have been generally similar to those reported by PansyMae although my breast development is much less impressive. As for brain rewiring, the phytoestrogen in PM works by bonding to estrogen receptors in the body, including the brain as well as the breasts so there are likely to be brain effects as well as boob effects! What these will be will vary fom person to person.
Note that 5-ARIs will only inhibit conversion of T to DHT, but probably do little to inhibit T production. I was prescribed spironolactone over an 18 month period, which does inhibit T production and seems to have finished off what was left of my male function, apparently permanently. Subsequently stopping PM and taking Butea superba and later tongkat ali for several months did little or nothing to restore function. I have a suspicion that taking Siterone (ciproterone) as proposed by PattiJT might have a similar effect in the long term.
Hope this helps.