31-03-2012, 07:07 PM
(30-03-2012, 07:51 AM)mochaccino Wrote: Poop!!I tried to research the side effects of forskolin and I could not find any evidence that it causes estrogen dominance in women or excess estrogen in men. Then I came across this extremely interesting thread: http://forum.bodybuilding.com/showthread.php?t=109108171&page=1
The first few posts are complete BS. The real juicy stuff starts at post 19 (the posts are numbered on the upper right) I would say sorry for bursting your bubble, but it's my bubble too. Oh well, there's always white peony. Hopefully my research on that will have better results.
This doesn't negate what you said about the mice. Too bad rodent results are so often irrelevant in humans, but at least there's a chance. How else might cAMP affect BE? This is where the endocrinology goes way over my head
So I went through the posts you mention and I don't think my bubble has been busted. On the contrary, please find attached a list of scientific articles which tend to indicate that forskolin does in fact increase aromatase activity and in fact in several of the studies they were using it to induce higher aromatase activity in cell lines so they could test an aromatase inhibiter. So my conclusion from this is it might or might not work but there are studies which provide evidence that it *does* work.
Personally I'm going to buy some and try it to see what the effects are combined with a DHT inhibitor.
http://www.ncbi.nlm.nih.gov/pubmed/9075722
http://www.unboundmedicine.com/medline/ebm/record/2821057/full_citation/Progestin_dependent_effect_of_forskolin_on_human_endometrial_aromatase_activity_
http://www.ncbi.nlm.nih.gov/pubmed/14623529
http://www.euro-endo.org/news/article.aspx?articleid=4461
http://www.experts.scival.com/georgia/pubDetail.asp?t=pm&id=1986609&
http://pages.aaps.org/elsevier/view.asp?ID=74525
http://www.ncbi.nlm.nih.gov/pubmed/20087668
http://www.frontiersin.org/10.3389/conf.fphar.2010.60.00162/event_abstract