17-02-2012, 06:49 AM
I hadn't heard of pueraria mirifica doing much other than being a very slight aromatase inhibitor but digging a little deeper it seems to do something very interesting.
According to this: http://www.ncbi.nlm.nih.gov/pubmed/21856387
it suppresses (does not block) 3β-HSD, 17β-HSD1, and CYP17 (17-alpha-hydroxylase) and CYP19 (aromatase) very slightly decreased but increases 17β-HSD2 to the same extent as estradiol.
What's interesting about that is that if taken in combination with DHEA it will force testosterone back to andrestenedione pathway which is more likely to give rise to estrone. It also appears to boost progesterone too which definitely helps breast growth.
If you take this along with aromatase boosters and 5-a-r blockers it looks like it's going to be very effective.
According to this: http://www.ncbi.nlm.nih.gov/pubmed/21856387
it suppresses (does not block) 3β-HSD, 17β-HSD1, and CYP17 (17-alpha-hydroxylase) and CYP19 (aromatase) very slightly decreased but increases 17β-HSD2 to the same extent as estradiol.
What's interesting about that is that if taken in combination with DHEA it will force testosterone back to andrestenedione pathway which is more likely to give rise to estrone. It also appears to boost progesterone too which definitely helps breast growth.
If you take this along with aromatase boosters and 5-a-r blockers it looks like it's going to be very effective.