[phatasssisssy]

Hi all!

I've been taking BO and pituitary since (fenugreek and maca a few weeks after) December 2025 and I've recently gotten on spironolactone. 

Does anyone know if BO diminishes the effects of the anti androgen? What about when I start estradiol? 

Anyone who started HRT please let me know their experience ?

Hello, 

Welcome to the forum! 

I've never been on BO. However, I started estradiol (oral, 2mg) and spironolactone (50mg) at the same time.

In the end though, oral E and spironolactone wasn't enough to get my hormone levels to cis female levels. Instead, I switched to injectional estradiol cypionate and Eligard to maximize feminization of my body.

Thanks girl!

I started with 100mg spiro and will go on estradiol in 2 months after next bloodwork. Its my doctor's strategy to lower the first then introduce E, which I'm happy with so long as my herbal routine doesn't diminish their effects.