4 hours ago
(5 hours ago)phatasssisssy Wrote: Hi all!
I've been taking BO and pituitary since (fenugreek and maca a few weeks after) December 2025 and I've recently gotten on spironolactone.
Does anyone know if BO diminishes the effects of the anti androgen? What about when I start estradiol?
Anyone who started HRT please let me know their experience ?
Hello,
Welcome to the forum!

I've never been on BO. However, I started estradiol (oral, 2mg) and spironolactone (50mg) at the same time.
In the end though, oral E and spironolactone wasn't enough to get my hormone levels to cis female levels. Instead, I switched to injectional estradiol cypionate and Eligard to maximize feminization of my body.

