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adults using only bicalutamide (casodex) alone?
#7

(21-09-2025, 02:19 PM)Heaven's Night Wrote:  
(21-09-2025, 12:34 PM)blackbirdordinary Wrote:  Have never seen anyone before suggest Bicalutamide as known more effective for the TransLater crowd. Your voluminous body of (results!) posts here leads me to believe you have more reasons to say that than purely personal experience. Can you share more about bica?

That study of teen trans women, plus the many studies of Bicalutamide in older men who mostly tolerate it very well are all that’s out there. But no studies of older trans women exist.

Am a four year lurker here, 48 year old bigender enby making my first post. Am seeking strong breast growth from my existing base top where I have always experienced gynecomastia, while maintaining bottom function.  As a bigender person, the plan is maintaining my assigned gender (m) identity, because is also gender affirming to me. (And yes, I am keenly aware of ED, taladafil, t creams and viagra for the bottom.) At the same time, this is not so much my fear of feminization so much as wanting to express both genders which I identify with fully, wholesomely and without terrible conflict (had enough conflict, thx!).

Haven’t taken anything yet, but had a first visit with my doctor and told them I wanted to try Bicalutamide mono therapy to accomplish these goals. They said it might not be enough for full breast development, but I told them it’s a marathon, not a sprint. Was not actually expecting the Doctor to agree with me so easily as they did. 

Can bica alone be enough, for the most part? Any tips from your experience?

Thank you for your many contributions to this board.

Hi! With this I would so much appreciate having Lotus chime in as she would know more than I do.

I would be quite confident about trying Bica as monotherapy, just make sure the doses stay moderate as Bica can be very stressful to liver, but afaik only if the doses are quite high.

Firstly, thank you for your response and for sharing your experiences Smile . Bicalutamide monotherapy is actually the path my Doctor recently blessed me to start exploring with baseline bloodwork. I'm hoping that it brings a level of mental clarity and relief not present during my many years of lurking here.

I have read everything great Lotus has to post on the issue of bicalutamide, and then some! It seems to be the path that fits my journey the best because of the route it takes to let the body produce its own E, so we can see the overall effects, while closely monitoring the liver's acceptance of the therapy. Fortunately, my heavy drinking days are well over a decade in my past, and my medically necessary diet changes have lowered my A1C and cholesterol significantly this year, too, which showed in my standard bloodwork. 

But this is a major step for me and one I do not consider lightly. Oh, and since I have gynecomastia already, and this is the BN, my gut tells me it should promote the kind of growth I'm looking for in my breasts.
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