I think its a good idea to do a sort of receptor reset when you're starting HRT, then after a while, start adding what pieces of NBE you want to it. I did with BO that I started from small dose, tested higher, went a bit down again and then worked my way up quite slowly. Same with other stuff, add one thing at a time on small doses and then work it up. You can then easily keep track of body changes and any side effects.

Like for example you could do changes or add things once or twice a month or so. I've noted fifteen days being the shortest time to tell if something's working or not. Typically it takes longer, but I have a tendency to react quickly.

Clean slate with starting labs is a good idea. There wont be anything messing it up so you can right away tell how well your HRT is working. Also keep in mind that estrogen etc., levels are not one size fits all situation, some doctors tend to read the numbers like its some ultimate truth on this when it really is not. Follow your body changes and mental state, that'll tell you quite a bit already.