05-01-2024, 06:19 AM
I lost 85lbs after having back surgery (I put that weight on pre-surgery, only to find out later I had leukemia). I lost maybe an inch off my breasts. I've gained back the inch of loss breast volume and then some. My current size is 52in bust with a 40in bust line. Estrogen is stored in fat cells, so losing weight combined with NBE or HRT makes for one helluva aromatase cocktail. It's action is via the process of lipolysis.
Lipolysis can be regulated through cAMP's binding and activation of protein kinase A (PKA). PKA can phosphorylate lipases, perilipin 1A, and CGI-58 to increase the rate of lipolysis. Catecholamines bind to 7TM receptors (G protein-coupled receptors) on the adipocyte cell membrane, which activate adenylate cyclase. This process above in essence triggers aromatase. Green tea extract is the only herb that I found to activate lipolysis.
https://en.m.wikipedia.org/wiki/Lipolysis#cite_note-8
Lipolysis can be regulated through cAMP's binding and activation of protein kinase A (PKA). PKA can phosphorylate lipases, perilipin 1A, and CGI-58 to increase the rate of lipolysis. Catecholamines bind to 7TM receptors (G protein-coupled receptors) on the adipocyte cell membrane, which activate adenylate cyclase. This process above in essence triggers aromatase. Green tea extract is the only herb that I found to activate lipolysis.
https://en.m.wikipedia.org/wiki/Lipolysis#cite_note-8