10-01-2023, 11:25 AM
As I take Hops 8pn for NBE, and I do a lot of reading, I wanted to point something out that I found in an article since there is discussion about bone loss.
8-Prenylnaringenin, which is the extract from hops can prevent osteoporosis and bone loss.
Quote from article:
"5. Prevention of Osteoporosis
Because osteoporosis is another unfavorable condition associated with menopause, the potential of 8-PN to prevent the loss of bone mass has been assessed [64,65]. In contrast to most other phytoestrogens that have been investigated for the treatment of menopause-related osteoporosis with disappointing results, 8-PN showed more favorable outcomes due to its preferential binding to ERα, which is predominant in bone tissue [66]. So far, the potential of 8-PN to prevent osteoporosis has been assessed using in vitro and in vivo models, but unfortunately, no clinical trials in humans have yet been conducted."
Link: https://www.mdpi.com/1420-3049/23/3/660
8-Prenylnaringenin, which is the extract from hops can prevent osteoporosis and bone loss.
Quote from article:
"5. Prevention of Osteoporosis
Because osteoporosis is another unfavorable condition associated with menopause, the potential of 8-PN to prevent the loss of bone mass has been assessed [64,65]. In contrast to most other phytoestrogens that have been investigated for the treatment of menopause-related osteoporosis with disappointing results, 8-PN showed more favorable outcomes due to its preferential binding to ERα, which is predominant in bone tissue [66]. So far, the potential of 8-PN to prevent osteoporosis has been assessed using in vitro and in vivo models, but unfortunately, no clinical trials in humans have yet been conducted."
Link: https://www.mdpi.com/1420-3049/23/3/660