04-11-2022, 09:05 AM
(04-11-2022, 04:53 AM)Lotus Wrote: My concern is the diosgenin in Wild Yam because it will compete with estradiol for estrogen receptor alpha (ER-A), even though it's nowhere the strength of estradiol. But it will compete with the PM. I wouldn't use the progesterone cream everyday as I pointed out earlier, and there's such a thing as dermal fatigue when using too much transdermal cream…meaning you build up a tolerance from continual use. If you're seeing a bump in growth see where it goes…diosgenin by itself does in fact stimulate breast growth. I have a science paper posted in the X-thread, use the search function and copy and paste this: diosgenin
So, use this product (3x per week) and monitor the results closely, if nothing happens it could be because of the diosgenin.
I'm... Personally not on PM actually! I'm on injections of EEN at the moment for my estrogen. Would that change that receptor interaction at all?
I'll keep this in mind though. When you say 3x a day though, is that applied to both breasts every 3 days? I imagine it would be, otherwise the progesterone mood swings may be messier.
If it's both breasts every 3 days, I'll do stagger it so I'll do each breast one day after the last, then hopefully I'll keep more even progesterone blood levels.
I've been on progesterone for the last week. Maybe a bit too much of it, hearing this, but I have seen what I imagine are positive effects so far.
Here's hoping we can find a more suitable progesterone cream sometime.

