[Lotus]

Question if I may ask, Lotus. I've been trying to search through threads on this forum for any mention of boron, since I've heard that can help with free E. Is there any research you've looked into or talked about in this thread? 400+ pages is a lot to look through.

Hi Siman, no worries, here's what I have on Boron. Incidentally, at the bottom of every thread is a search function, simply insert your search term and "presto" ? you'll have every post that I've talked about that certain topic. Btw, there's other ways to improve free E2 percentage, like reducing daily carbohydrates and sugar intake (insulin). Make sure to get free E2 tested next week too. Concerning my own free E2 percentage, as the PA ( Physicians Assistant) at my doctors office told my free E2 was very good at 1.6%. Rarely is someone at 2% (the optimal level).

My latest test results came back as follows:

E2  386 pg/mL 
Free  E2 1.6%
TT  45 ng/dL 
DHT  41 ng/dL. ( reference range 12-65 ng/dL)
SHBG  131 nmol/
Progesterone  18 ng/mL
FSH  0.7 mIU/mL
LH  0.2 mIU/mL
3A-androstanediol glucuronide....298ng/dL  ref range 425-3230 ng/dL 

This is the backdoor androgen and the subsequent test leaking from progesterone to DHT. My level at 298 ng/dL is well below the reference range even using Dr. Powers Testosterone Atrophy cream @ .50mg (the stuff really works), though it raised my TT (total Testosterone and DHT), it restored girth and length, i use 1x per week for for the past 3 months alongside my hrt program. My purpose for using it is in preparation for bottom surgery. If you use this cream for the same purpose plan on either laser/electrolysis one year out prior to surgery and opt for Dr. Powers pain cream (25% lidocaine)or similar. I believe you need to be a Powers patient.

Great thread, recently starting taking Boron worried about heavy metals, and I do the liver detox every other month. So I added MSM and Boron. I think every other day for the standard low does Boron fine and how much and at what time to take MSM?..I saw this thread on the web, jumped back, did a search and found this thread, thanks again Lotus.
https://sci-hub.tw/https://www.ncbi.nlm.nih.gov/pubmed/24268550 and
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1566640/

Hi happyboobs, 

I've seen boron dosages at between 3 mg to 20mg, as with any new supplement one needs to start slowly, (e.g. starting at 3mg and see how your body reacts to it). The study I linked on boron found results using 3mg. There's no RDA (recommended daily allowance), so proceed with caution. My thoughts on how to use boron for NBE is that if your T is above 100 ng/dL you'll need to take an anti-androgen to see an increase in E2. And if T is consistently below 50ng/dL maybe you supplement with a pro-aromatase, (my preference is Forskolin and or white peony.

• Two things from the study sticks out for me,
1) boron regulates the messenger RNA (mRNA) expression of a wide range of extracellular-matrix proteins

2) Boron doubles E2 expression in men and women, but it took 4 weeks. 

(also from the study)
In women on a low-magnesium diet, E2 almost doubled, increasing from an average of 21.1 pg/mL to 41.4 pg/mL. Testosterone more than doubled, rising from an average of 0.31 ng/mL to 0.83 ng/mL. Similar increases were seen in the women on an adequate-magnesium diet: E2 rose from an average of 15.5 pg/mL to 38.0 pg/mL, and testosterone increased from 0.38 ng/mL to 0.65 ng/mL. In 1997, Naghii et al21 published findings of a similar increase in serum levels of E2 in healthy males (n = 18) after 4 weeks of dietary supplementation with boron.

As far as when to supplement MSM (and how much) is taking it in the evening, preferably at bedtime, and 2-3 grams (that's 2,000mg to 3,000mg). And I'll explain further in the next post why supplementing at bedtime makes more sense for a growth phase to happen versus daytime phase supplementing hopefully tonight. 
@ spanky... I love to dance   
@ Valkyrie...you smart girl lol, be very careful with Fenugreek, it'll drop blood glucose fast, too fast in certain groups, meaning hypoglycemia, and very bad for diabetics. Also, if you have nut allergies you'd better stay away from fenugreek. 

As with any supplements, source organic when possible and clean ingredients, meaning non-gmo, no rice flour, no maltodextrin or dextrose, all of which spikes insulin. Spiking daytime insulin is bad for boobs imho... which I'll outline in the next post. Adding maltodextrin to Stevia makes no sense whatsoever to me, (stevia is a low-calorie sweetener that has antioxidant and antidiabetic properties. It reduces hunger and improves satiety, which is undone by adding maltodextrin, just saying lol). 

@troublewithnibbles, I'm very intrigued by your question in the anti-androgens thread (can't wait till I can answer that one), I can't remember ever being asked that, what a great question though.

Some more informations about Boron:

Boron affects the metabolism of steroid hormones, and especially of sex hormones. It increases low testosterone levels in men and oestrogen levels in menopausal women. It also has a role in converting vitamin D to its active form, thus increasing calcium uptake and deposition into bone and teeth rather than causing soft tissue to calcify. Also other beneficial effects have been reported such as improvement of heart problems, vision, psoriasis, balance, memory and cognition.

The German cancer researcher Dr Paul-Gerhard Seeger has shown that cancer commonly starts with the deterioration of cell membranes. As boron is essential for cell membranes and boron deficiency widespread, this may be an important cause for the initiation of tumor growth. Boron compounds have anti-tumour properties and are "potent anti-osteoporotic, anti-inflammatory, hypolipemic, anticoagulant and anti-neoplastic agents" 

http://www.health-science-spirit.com/borax.htm

- Boron was shown to have reduced the incidence of prostate cancer development by 64%

- Non Toxic: Doses up to 18mg of boron daily appear to be safe for adults even if taken for prolonged periods of time.

- Helps in production of estrogen. Boron might improve the production of estrogen in menopausal women, bringing back their sex drive within a few days of treatment. Boron increases the level of natural sex hormones in the body, thereby reducing the need for Hormone replacement therapy.
https://docs.google.com/document/d/1Gyso...ggAmo/edit

Great find Peggy, the daily multi-vitamin I take lists 150 mcg. of Boron. The google link has some pretty interesting uses for boron, (sleep aid, pain and detox I didn't know).
 
Thanks