Hey HandofFate, I believe your current program has conflict, and I'll explain. Let's take phosphatidylserine for instance:
(PS) is a phospholipid that contains both amino acids and fatty acids. The omega-3 fatty acids EPA and DHA work synergistically with PS to provide the building blocks for healthy cell membranes.
What Is Phosphatidylserine? (Top 6 Benefits & How to Use It)
https://draxe.com/nutrition/phosphatidylserine/
Phosphatidylserine is an interesting choice in one's program, however I think it's redundant to take amino acid protein drinks @ 30g/day in addition. Too much protein can spike insulin and thereby spike T and reduce adenylyl cyclase production…and we don't want to inhibit the latter because it's essential for gene expression to grow breasts. Taking Phosphatidylserine seems to be okay, just drop the additional protein.
I'd lower MSM to 3 grams per day, that's just me though.
What kind of collagen do you take? I need the supplemental ingredients information.
What kind of vitamin C do you take?, 1 gram per day is way too much. Seeing that ascorbic acid is synthetically made, probably using corn starch, corn syrup, glucose and maltodextrin, I'd skip the synthetic version and get it naturally in a daily diet. My choice is lemons and peppers.
Are you taking ashwagandha to reduce stress?. The following research paper describes that T levels in males increased. Based on your labs you aren't a male anymore though. Ashwagandha also lowers the HPA (hypothalamus pituitary axis) vis lowered cortisol, I'm not sure how lowering HPA axis is beneficial for breast growth just yet, I'll let you know. I never cared for saw palmetto, and this DHT blocker has saw palmetto. Research on SP indicates it inhibits progesterone receptors and inhibits estrogen. SP inhibits DHT around 25%...as an example dutasteride inhibits DHT around 95-98%. The DHT blocker has some good ingredients like green tea extract and catechines.
An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract
Ashwagandha intake was also associated with greater reductions in morning cortisol (P < .001), and DHEA-S (P = .004) compared with the placebo. Testosterone levels increased in males (P = .038) but not females (P = .989) over time, although this change was not statistically significant compared with the placebo (P = .158).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC67502
Taking Bountiful breast pills is said to stimulate the pituitary, this would be in conflict with taking ashwagandha as it lowers the pituitary function.
Taking L-Arginine increases nitric oxide production (good for breast growth) and is a vasodilator which creates more blood flow to tissues.
No issues with the calcium and melatonin unless it's calcium carbonate (which is harsh on the stomach and less bioactive), I prefer calcium citrate:
https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/calcium-supplements/art-20047097
Calcium and calcium supplements: Achieving the right balance
To absorb calcium, your body also needs vitamin D.
Absorbability
Your body must be able to absorb the calcium for it to be effective. All varieties of calcium supplements are better absorbed when taken in small doses (500 mg or less) at mealtimes. Calcium citrate is absorbed equally well when taken with or without food and is a form recommended for individuals with low stomach acid (more common in people over 50 or taking acid blockers), inflammatory bowel disease or absorption disorders.
https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/calcium-supplements/art-20047097
The DHT blocker combo has ingredients that inhibit aromatase (grape seed extract). Nettle root isn't my choice either, it's unpredictable for stimulating T or E2…I'd skip this one and opt for dutasteride. I didn't like taking AA's, especially finasteride as it's a neuro-steroid that promotes depressive states. Plus, there's such a thing called finasteride syndrome which takes months to get over, so I opted for an orchidectomy. You'll never hear me recommend getting an orchidectomy, this is a personal choice with life long repercussions (or benefits depending on who you ask).
I'm listing a ton of information on using MK-677, my own personal feeling is no one should use it for growing breasts…it simply doesn't work at growing breasts. Please read the attached links (as there are many) and judge for yourself. On a side note MK-677 creates lean body mass as opposed to creating fat mass, which in my opinion is a conflict to gaining weight needed for increased adipose tissue in breasts.
Berberine is like an herbal version of metformin. Taking it increases AMPK and ATP production. Increasing AMPK production helps to regulate energy, food intake and increases in cAMP levels (via cGMP concentration) inhibits the PDEs that inhibit (degrades) cAMP thus promoting adenylyl cyclase which increases the potential for gene expression...basically it helps promote breast growth in the nucleus of estrogen receptors.
Definitions
cyclic adenosine monophosphate (cAMP)
3′-5′-cyclic guanosine monophosphate(cGMP)
cyclic nucleotide phosphodiesterases (PDEs)
AMP-activated protein kinase (AMPK)
ATP (adenosine triphosphate phosphate)
Your labs indicate good levels of E and T. Taking weekly (7 days) injections of estradiol valerate at 5mg to 10mg is considered normal dosage. How do fit .9mL of estradiol valerate into a 1mL syringe? I'd be concerned about spillage coming from the plunger? . Your lab report indicates a modest 248.8 pg/ml of estradiol using 9mg, though resolving some of the above mentioned conflicts should raise the estradiol on your next lab. Discuss all the things you take with your doctor, see what he advises.
Stopping progesterone completely is probably a good idea till you sort things out. I don't see an issue with using the noogleberry daily…though not for hours, 15 to 30 minutes is all I ever did.
MSM 4grams/day
collagen 7 grams/day
slow release vitamin C 1gram/day
phosphatidylserine 400mg/day
ashwagandha 500mg/day (going to increase)
Bountiful Breast green pills 2pills twice a day
amino acid protein drink 30g/day
L-Arginine 1gram/day
calcium 600mg
melatonin 5mg
DHT blocker combo from amazon
Estradiol Valerate 9mg/week
Progesterone as suppository 200mg/week
MK677 50mg daily
Berberine 2400mg/day
noogleberry every day for hours
I posted this information in the x-thread sometime ago:
On inhibiting somatostatin, it's in breast growers interest to inhibit its action. Meaning when somatostatin is released it inhibits prolactin, oral estradiol, adenylyl cyclase, growth hormone and TSH (thyroid releasing hormone)...which also inhibits TRH (Thyrotropin releasing hormone). And inhibiting TRH means no prolactin production. In other words prolactin stimulates the aveolargenesis in the lobules of breasts. Vitamin D3 and MSM are very important for alveolar stimulation.
When you inhibit adenylyl cyclase you inhibit ATP production, and the end result of that is inhibiting aromatase. See, estrogen stimulates prolactin and growth hormone, so by somatostatin inhibiting their action it seems like an awful waste for breast growth.
Somatostatin
https://www.sciencedirect.com/topics/neuroscience/somatostatin
MK-0677 (ibutamoren mesylate) for the treatment of patients recovering from hip fracture: A multicenter, randomized, placebo-controlled phase IIb study:
Author links open overlay panel Abraham AdunskyaDimitris A.Papanicolaoub
https://doi.org/10.1016/j.archger.2010.10.004Get rights and content
Abstract
Most elderly patients admitted for hip fracture suffer functional decline. Previous studies with MK-0677 in hip fracture patients suggested possible benefits to functional recovery. This is a randomized, double-blind study of 123 elderly hip fracture patients assigned to receive 25 mg/day of MK-0677 (n = 62) or placebo (n = 61). Primary outcomes were a rank analysis of change during the study in objective functional performance measurements and insulin-like growth factor-1 (IGF-1) levels in blood. At 24-weeks, the mean stair climbing power increased by 12.5 W in the MK-0677 group (95% confidence interval (CI) = −10.95–35.88; p = 0.292) compared with placebo. Gait speed increased by a 0.7-score difference in the means (95% CI = 0.17–1.28; p = 0.011). There was no improvement in MK-0677 treated patients in several other functional performance measures. The MK-0677 group experienced fewer falls during the study compared to placebo and a smaller number of patients who had any falls (p = 0.096). Levels of IGF-1 in treated patients increased by 51.4 ng/ml (95% CI = 34.42–68.44; p < 0.001) compared to placebo. Trial was terminated early due to a safety signal of congestive heart failure in a limited number of patients. In hip fracture patients treated with 25 mg/day MK-0677, the increase in plasma IGF-1 levels was not paralleled by improvement in most functional performance measures. MK-0677 has an unfavorable safety profile in this patient population.
https://www.sciencedirect.com/science/article/abs/pii/S0167494310002530
Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial
https://pubmed.ncbi.nlm.nih.gov/19015485/
Mk-677 discussed at Breastnexus
https://www.breastnexus.com/showthread.php?tid=22417&pid=208328&highlight=mk-677#pid208328
Mk-677 discussed at Breastnexus
https://www.breastnexus.com/showthread.php?tid=27347&page=7
Mk-677 discussed at Breastnexus
https://www.breastnexus.com/showthread.php?tid=22417&page=18&highlight=mk-677
Finally
On being called a troll, your delivery to others is abrasive and mean spirited sometines. Folks generally try to help you here, if you don't agree with the advice you don't get to throw them under the bus. I've even questioned your real intent here based on dealings with people. Do you enjoy causing turmoil with certain people? If so, that makes you a troll in my book and you should be sent packing.
As witnessed here:
(PS) is a phospholipid that contains both amino acids and fatty acids. The omega-3 fatty acids EPA and DHA work synergistically with PS to provide the building blocks for healthy cell membranes.
What Is Phosphatidylserine? (Top 6 Benefits & How to Use It)
https://draxe.com/nutrition/phosphatidylserine/
Phosphatidylserine is an interesting choice in one's program, however I think it's redundant to take amino acid protein drinks @ 30g/day in addition. Too much protein can spike insulin and thereby spike T and reduce adenylyl cyclase production…and we don't want to inhibit the latter because it's essential for gene expression to grow breasts. Taking Phosphatidylserine seems to be okay, just drop the additional protein.
I'd lower MSM to 3 grams per day, that's just me though.
What kind of collagen do you take? I need the supplemental ingredients information.
What kind of vitamin C do you take?, 1 gram per day is way too much. Seeing that ascorbic acid is synthetically made, probably using corn starch, corn syrup, glucose and maltodextrin, I'd skip the synthetic version and get it naturally in a daily diet. My choice is lemons and peppers.
Are you taking ashwagandha to reduce stress?. The following research paper describes that T levels in males increased. Based on your labs you aren't a male anymore though. Ashwagandha also lowers the HPA (hypothalamus pituitary axis) vis lowered cortisol, I'm not sure how lowering HPA axis is beneficial for breast growth just yet, I'll let you know. I never cared for saw palmetto, and this DHT blocker has saw palmetto. Research on SP indicates it inhibits progesterone receptors and inhibits estrogen. SP inhibits DHT around 25%...as an example dutasteride inhibits DHT around 95-98%. The DHT blocker has some good ingredients like green tea extract and catechines.
An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract
Ashwagandha intake was also associated with greater reductions in morning cortisol (P < .001), and DHEA-S (P = .004) compared with the placebo. Testosterone levels increased in males (P = .038) but not females (P = .989) over time, although this change was not statistically significant compared with the placebo (P = .158).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC67502
Taking Bountiful breast pills is said to stimulate the pituitary, this would be in conflict with taking ashwagandha as it lowers the pituitary function.
Taking L-Arginine increases nitric oxide production (good for breast growth) and is a vasodilator which creates more blood flow to tissues.
No issues with the calcium and melatonin unless it's calcium carbonate (which is harsh on the stomach and less bioactive), I prefer calcium citrate:
https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/calcium-supplements/art-20047097
Calcium and calcium supplements: Achieving the right balance
To absorb calcium, your body also needs vitamin D.
Absorbability
Your body must be able to absorb the calcium for it to be effective. All varieties of calcium supplements are better absorbed when taken in small doses (500 mg or less) at mealtimes. Calcium citrate is absorbed equally well when taken with or without food and is a form recommended for individuals with low stomach acid (more common in people over 50 or taking acid blockers), inflammatory bowel disease or absorption disorders.
https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/calcium-supplements/art-20047097
The DHT blocker combo has ingredients that inhibit aromatase (grape seed extract). Nettle root isn't my choice either, it's unpredictable for stimulating T or E2…I'd skip this one and opt for dutasteride. I didn't like taking AA's, especially finasteride as it's a neuro-steroid that promotes depressive states. Plus, there's such a thing called finasteride syndrome which takes months to get over, so I opted for an orchidectomy. You'll never hear me recommend getting an orchidectomy, this is a personal choice with life long repercussions (or benefits depending on who you ask).
I'm listing a ton of information on using MK-677, my own personal feeling is no one should use it for growing breasts…it simply doesn't work at growing breasts. Please read the attached links (as there are many) and judge for yourself. On a side note MK-677 creates lean body mass as opposed to creating fat mass, which in my opinion is a conflict to gaining weight needed for increased adipose tissue in breasts.
Berberine is like an herbal version of metformin. Taking it increases AMPK and ATP production. Increasing AMPK production helps to regulate energy, food intake and increases in cAMP levels (via cGMP concentration) inhibits the PDEs that inhibit (degrades) cAMP thus promoting adenylyl cyclase which increases the potential for gene expression...basically it helps promote breast growth in the nucleus of estrogen receptors.
Definitions
cyclic adenosine monophosphate (cAMP)
3′-5′-cyclic guanosine monophosphate(cGMP)
cyclic nucleotide phosphodiesterases (PDEs)
AMP-activated protein kinase (AMPK)
ATP (adenosine triphosphate phosphate)
Your labs indicate good levels of E and T. Taking weekly (7 days) injections of estradiol valerate at 5mg to 10mg is considered normal dosage. How do fit .9mL of estradiol valerate into a 1mL syringe? I'd be concerned about spillage coming from the plunger? . Your lab report indicates a modest 248.8 pg/ml of estradiol using 9mg, though resolving some of the above mentioned conflicts should raise the estradiol on your next lab. Discuss all the things you take with your doctor, see what he advises.
Stopping progesterone completely is probably a good idea till you sort things out. I don't see an issue with using the noogleberry daily…though not for hours, 15 to 30 minutes is all I ever did.
MSM 4grams/day
collagen 7 grams/day
slow release vitamin C 1gram/day
phosphatidylserine 400mg/day
ashwagandha 500mg/day (going to increase)
Bountiful Breast green pills 2pills twice a day
amino acid protein drink 30g/day
L-Arginine 1gram/day
calcium 600mg
melatonin 5mg
DHT blocker combo from amazon
Estradiol Valerate 9mg/week
Progesterone as suppository 200mg/week
MK677 50mg daily
Berberine 2400mg/day
noogleberry every day for hours
I posted this information in the x-thread sometime ago:
On inhibiting somatostatin, it's in breast growers interest to inhibit its action. Meaning when somatostatin is released it inhibits prolactin, oral estradiol, adenylyl cyclase, growth hormone and TSH (thyroid releasing hormone)...which also inhibits TRH (Thyrotropin releasing hormone). And inhibiting TRH means no prolactin production. In other words prolactin stimulates the aveolargenesis in the lobules of breasts. Vitamin D3 and MSM are very important for alveolar stimulation.
When you inhibit adenylyl cyclase you inhibit ATP production, and the end result of that is inhibiting aromatase. See, estrogen stimulates prolactin and growth hormone, so by somatostatin inhibiting their action it seems like an awful waste for breast growth.
Somatostatin
https://www.sciencedirect.com/topics/neuroscience/somatostatin
MK-0677 (ibutamoren mesylate) for the treatment of patients recovering from hip fracture: A multicenter, randomized, placebo-controlled phase IIb study:
Author links open overlay panel Abraham AdunskyaDimitris A.Papanicolaoub
https://doi.org/10.1016/j.archger.2010.10.004Get rights and content
Abstract
Most elderly patients admitted for hip fracture suffer functional decline. Previous studies with MK-0677 in hip fracture patients suggested possible benefits to functional recovery. This is a randomized, double-blind study of 123 elderly hip fracture patients assigned to receive 25 mg/day of MK-0677 (n = 62) or placebo (n = 61). Primary outcomes were a rank analysis of change during the study in objective functional performance measurements and insulin-like growth factor-1 (IGF-1) levels in blood. At 24-weeks, the mean stair climbing power increased by 12.5 W in the MK-0677 group (95% confidence interval (CI) = −10.95–35.88; p = 0.292) compared with placebo. Gait speed increased by a 0.7-score difference in the means (95% CI = 0.17–1.28; p = 0.011). There was no improvement in MK-0677 treated patients in several other functional performance measures. The MK-0677 group experienced fewer falls during the study compared to placebo and a smaller number of patients who had any falls (p = 0.096). Levels of IGF-1 in treated patients increased by 51.4 ng/ml (95% CI = 34.42–68.44; p < 0.001) compared to placebo. Trial was terminated early due to a safety signal of congestive heart failure in a limited number of patients. In hip fracture patients treated with 25 mg/day MK-0677, the increase in plasma IGF-1 levels was not paralleled by improvement in most functional performance measures. MK-0677 has an unfavorable safety profile in this patient population.
https://www.sciencedirect.com/science/article/abs/pii/S0167494310002530
Growth hormone secretagogue MK-677: no clinical effect on AD progression in a randomized trial
https://pubmed.ncbi.nlm.nih.gov/19015485/
Mk-677 discussed at Breastnexus
https://www.breastnexus.com/showthread.php?tid=22417&pid=208328&highlight=mk-677#pid208328
Mk-677 discussed at Breastnexus
https://www.breastnexus.com/showthread.php?tid=27347&page=7
Mk-677 discussed at Breastnexus
https://www.breastnexus.com/showthread.php?tid=22417&page=18&highlight=mk-677
Finally
On being called a troll, your delivery to others is abrasive and mean spirited sometines. Folks generally try to help you here, if you don't agree with the advice you don't get to throw them under the bus. I've even questioned your real intent here based on dealings with people. Do you enjoy causing turmoil with certain people? If so, that makes you a troll in my book and you should be sent packing.
As witnessed here:
(04-06-2022, 05:24 AM)HandofFate Wrote: You want me to inject 0.45 ml into my fat and give me a blister ? Wtf is wrong with you. You are the troll here.I have done the 7mg/5 days.
I have done many regimens. My doctor wants me on 9mg/week I have shown you the trough from 10mg/week.
I have tried the creamer diet and it did nothing for my chest.