02-01-2021, 10:38 PM
(05-12-2020, 08:03 PM)jannet.duff Wrote:(30-11-2020, 09:20 PM)pear Wrote:I think I've read somewhere on this Breast Nexum that the liver filters out 80% of any swallowed dosage; whereas via the suppository method 100% enters your bloodstream. Is this correct?
Maybe not quite that amount, but yes.
That's why injections on HRT, is seen as the best option.
Most of us take our progesterone capsules through
the back door for the same reason.
Since I first started this thread I've tried various suppository dosages from 3x250mg daily for a few days to just 1x250mg daily. I find that 250mg daily is sufficient for results I might even try a bit less. When I tried 3x250mg daily it made me feel uncomfortable and I had difficulty sleeping.

