30-10-2019, 12:10 PM
(13-10-2019, 05:07 PM)Stevenator Wrote: 1,000mg of Tagamet (Cimetidine) a day will do it.
>While researching Cimetidine (Tagamet) tonight I found a ton of articles stating that it does significantly increase prolactin, it does cause gynecomastia in men.
Cimetidine is a known testicular toxicant as indicated by significantly reduced weight of male sex organs, and it causes gynecomastia in males”.
I wasn’t imagining things tonight. My entire package has shrunk significantly. In just three short days it’s 1/2 the size of what it was. Bear in mind, this is at a 1,000mg dose per day, based on stated high doses that resulted in gynecomastia.
The study goes on to say that it causes the cessation of spermatogenesis.
Like the article mentioned, I noticed an immediate effect on loss of libido & sexual function. “The prolactin response in males is swift and occurs in association with high circulating concentration of cimetidine”.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040935/
Had a quick look at Cimetidine. I've never use that in particular (for it's intended purpose) but I have experienced the negative impact of other anti histimines when it comes to achieving orgasm (damn near impossible while taking them).
Looks like histimine plays a crucial role in achieving erections (https://www.ncbi.nlm.nih.gov/pubmed/7850330) so some effective histimine blockers would no doubt negatively impact erections (although I wouldn't assume in a permanent way).