Calorie Restriction in Male Mice Feminizes Gene Expression

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Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory Pathways

Our data show that CR induces widespread gene expression changes and acts through highly evolutionarily conserved pathways, from microorganisms to mammals, and that its life-extension effects might arise partly from a shift toward a gene expression profile more typical of females

These results suggest that CR has a generally feminizing effect on gene expression

http://journals.plos.org/plosone/article...ne.0005242

I mentioned in another post that someone once mentioned that the most significant thing they ever did to feminize themselves and feel more feminine was to lose weight. This study suggests there might be more at play behind the scenes (in terms of feminization) than simply losing the weight.