[tanysquirrel]

Hormonal breast enhancement

https://en.wikipedia.org/wiki/Hormonal_b...nhancement

some herbal breast enlargement supplements contain phytoestrogens such as 8-prenylnaringenin (found in hops) and miroestrol (a constituent of Pueraria mirifica) and thus may be regarded as a form of hormonal breast enhancement.[3] However, evidence of their effectiveness, as well as safety data, are lacking.
Hormonal manipulation and breast growth

research has found that girls with growth hormone deficiency (GHD) who are treated with GH experience accelerated breast growth[25] and that boys with GHD treated with GH sometimes experience gynecomastia.[26] Moreover, IGF-1 levels and activity have been found to be correlated with breast volume in the female general population.

Certain long-acting growth hormone secretagogues, such as CJC-1295[30] and ibutamoren (MK-677),[31] are capable of reliably and effectively increasing serum GH and IGF-1 concentrations in humans.[32][33][34] Alternatively, exogenous, pharmaceutical GH and IGF-1 (as mecasermin or mecasermin rinfabate) themselves, or analogues of IGF-1 such as des(1-3)IGF-1 and IGF-1 LR3, may be employed to increase GH/IGF-1 axis function. .[35][36][37][38][39] Vitamin D has been found to increase IGF-1 levels in both healthy subjects and individuals with GHD, and vitamin D deficiency is associated with low IGF-1 levels.[40][41][42] However, there is evidence that vitamin D may also potently inhibit breast growth via activation of the vitamin D receptorA number of dietary supplements, including L-arginine, L-ornithine, L-lysine, acetyl-L-carnitine, and creatine, may be able to significantly increase GH levels, although evidence is mixed

to a lesser extent, medroxyprogesterone acetate (MPA), when taken orally, induce IGF-1 production via activation of the androgen receptor (AR) in the liver.

Cyclooxygenase-2 (COX-2) overexpression in mammary gland tissue produces mammary gland hyperplasia as well as precocious mammary gland development in female mice, indicating a strong stimulatory effect of this enzyme on the growth of the mammary glands.[65][66] These effects appear to be downstream actions of increased activation of the prostaglandin EP2, EP3, and EP4 receptors, but not the EP1 receptor, in mammary gland tissue, which in turn results in the potent induction of amphiregulin expression, a critical growth factor involved in normal mammary gland development.[65][66] In addition, agonists of the epidermal growth factor receptor (EGFR), the molecular target of amphiregulin, induce COX-2 expression in mammary gland tissue, potentially resulting in a self-perpetuating cycle of growth amplification by COX-2.[65][66] This mechanism is closely related to formation, growth, and spreading of cancers with poor prognosis, and is in accordance with the fact that long-term administration of aspirin, a COX inhibitor, as well as of other COX-inhibiting non-steroidal anti-inflammatory drugs (NSAIDs), have been found to slightly reduce the risk of breast cancer in women (it is notable here that breast growth/size and breast cancer risk are positively associated).[67] Taken together, these findings indicate that COX-2 inhibitors, such as aspirin, ibuprofen, naproxen, paracetamol (acetaminophen), and celecoxib, may suppress growth of breast tissue.[65][66]


so..if you want breast growth, increase the igf-1, and try not to take any pain pills , asprin etc.