[tanysquirrel]

interesting re: Pueraria mirifica

worth the read :
http://www.multibriefs.com/briefs/acam/ACAM_Newsletter_8_13_13_Article_Fleisher.pdf

" strong anti-mutagenic properties  anti-carcinogenic effects, esp. among breast cancer and colon cancer lines  relatively safe control of perimenopausal and postmenopausal symptoms, i.e., vasomotor instability, hot flashes, night sweats, and mood changeability, similar to effects exhibited by conjugated equine estrogens, but without the toxicity  prevention and improvement of osteopenia and osteoporosis in both sexes  significant improvement of blood lipid and cholesterol levels  enhanced function of the endothelial lining of blood vessels  cardiovascular protective properties  prevention and reduction of prostate hyperplasia  prevention and reduction of erectile dysfunction  mammogenic effects, i.e., natural promotion of enlargement, toning and firming of the female breasts, by stimulating healthy, breast gland fibroblastic activity'- this would explain why some people maintain erections on it or they come back?

more: Current scientific research recognizes that there are two types of estrogen cell surface receptors, the alpha receptor (ERa) and beta receptor (ERb). ERa affects classical, estrogen sensitive tissues, e.g., breasts, uterine endometrium, ovarian stromal cells, male testes and vas deferens, and the hypothalamus in the brain. Whereas, ERb affects non-classical, estrogen sensitive tissues, e.g., brain, bone, heart, lungs, kidneys, intestinal mucosa, and vascular endothelium in both sexes.
Excessive ERa stimulation can lead to breast cancer and other estrogen-dependent cancers. Competitive inhibition of ERa receptors by phytoestrogens, via blocking the binding of the stronger, estrogenic hormones, i.e., estrone and estradiol, can help protect against the development of estrogen-dependent cancers of the breast, uterus, ovaries and prostate. This is the physiochemical basis for the anti-carcinogenic effect of soy isoflavones, and various other naturally occurring phytoestrogens.
Phytoestroegns from various plant sources may either activate or inhibit ERa and/or ERb receptors. Miroestrol and deoxymiroestrol in Pueraria preferentially powerfully stimulate ERb receptors, and inhibit ERa receptors. Miroestrol and its derivatives are known to be approximately 3,000 times more potent than soy isoflavones with respect to estrogen receptor effects.
ERb stimulation in the brain has been shown to protect neuronal cells from injury and death from excitotoxins, e.g., MSG. ERb stimulation in the prostate gland helps protect against hyperplasia, and reduce symptoms of benign enlargement of the prostate.
Pueraria mirifica may constitute a new class of safe, non-toxic, effective, hormonal therapeutic support as natural, Selective Estrogen Receptor Modulators (SERMs), with estrogen agonist activity in certain tissues and antagonist activity in others, which help balance hormonal function, and possess significant, anti-aging, protective properties for estrogen sensitive tissues in both men and women.'

so it is my understanding,that.. in activating the ERb , your are creating the negative feedback loop in the hypothalamus, leading to the aromatization of testosterone? since the ERb have to do with brain barrier and such.. according to this article, PM inhibits the ERa activity, which has to do with the breasts directly.. so it would seem that the PM is a "backdoor" method of getting the endocrine system to feminize the biomale? So its not adding breasts by estrogen, its telling the body to convert T into E.. am I wrong?