[Lotus]

The middle paragraph is profound imo, in other words, FAT has a mix of a few androgens, a couple co-regulators of hormones, pro growth hormone (IGF-1/insulin), a couple pro-estrogen factors..........and another regulator of how fat is mobilized (rather metabolized) aka P450 cytochrome family of enzymes. Key word here is mobilizing fat......you know lol, using our fat as an NBE supplement (that's absolutely free).



Several steroidogenic enzymes are expressed in adipose tissue including cytochrome P450-dependent aromatase , 3 -hydroxysteroid dehydrogenase (HSD), 3 HSD, 11 HSD1, 17 HSD, 7 -hydroxylase, 17 -hydroxylase, 5 - reductase, and UDP-glucuronosyltransferase 2B15 (71, 72).

Given the mass of adipose tissue, the relative contribution of adipose tissue to whole body steroid metabolism is quite significant, with adipose tissue contributing up to 100% of circulating estrogen in postmenopausal women and 50% of circulating testosterone in premenopausal women.

Although the adrenal gland and gonads serve as the primary source of circulating steroid hormones, adipose tissue expresses a full arsenal of enzymes for activation, interconversion, and inactivation of steroid hormones.
http://www.iub.edu/~k662/articles/obesit...202004.pdf