13-03-2016, 03:09 AM
∗∗ 100 g of P. mirifica contains an average of 15mg of Miroestrol:
1mg of crude P. mirifica = o.5 μg Ethyl Estradiol
1g of crude P. mirifica = (0.5)(1000 μg Ethyl Estradiol)
Therefore:
100 g of crude P. mirifia = (0.5)(1000)(100 μg Ethyl Estradiol)
100 g of crude P. mirifica = 50,000 μg Ethyl Estradiol
100 g of crude P. mirifica has 15 mg of Miroestrol.
15 mg of Miroestrol = 50,000 μg Ethyl Estradiol
1 mg of Miroestrol = (50,000)/(15 μg Ethyl Estradiol)
1 mg of Miroestrol = 3333.33 μg Ethyl Estradiol
(Same pdf)
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1mg of crude P. mirifica = o.5 μg Ethyl Estradiol
1g of crude P. mirifica = (0.5)(1000 μg Ethyl Estradiol)
Therefore:
100 g of crude P. mirifia = (0.5)(1000)(100 μg Ethyl Estradiol)
100 g of crude P. mirifica = 50,000 μg Ethyl Estradiol
100 g of crude P. mirifica has 15 mg of Miroestrol.
15 mg of Miroestrol = 50,000 μg Ethyl Estradiol
1 mg of Miroestrol = (50,000)/(15 μg Ethyl Estradiol)
1 mg of Miroestrol = 3333.33 μg Ethyl Estradiol
(Same pdf)
__________________________
Quote:P. mirifica was reported in the literature to have estrogenic-like properties as early as 1940.(Schoeller, W., Dohrn, M. ned Hohlweg, Naturwiss., 1940; 28: 532; and, Butenandt, A. Naturwiss., 1940; 28: 533; and, Bradbury, R.B. and White, D.E. Estrogens and related substances in plants. Vitamins Hormones, 1954; 12: 207-233.)
References for compounds characterized in P. mirifica: Murakami, T., Nishikawa, Y. and Ando, T. Studies on the Constituents of Japanese and Chinese Crude Drugs. IV. On the constituents of Pueraria root. Chem Pharm Bull Tokyo., 1960;