[Lotus]

Hi spanky, happyme and crew.

Reduced sperm (quite possibly permanently). Dustasteride inhibits two types of 5 alpha reductase (type I & II), it'll tank total and free T. It looks like it has a surge (of T) in the first 30-45 days, most likely from negative feedback of lutenizing hormone. This surge (or flare as they say) also happens to a lesser extent when starting PM, and from my experience BO did the same thing at first. Lowered T can have a strong impact on libido, lowered free T will impact penis size.
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Lotus,
That makes the mad scientist in me wonder, could we "manage" free T, increase E, and in essence make the best of both worlds?
I somewhat doubt it, but, would be interesting to look into it.
Eventually, though, the E kills the T (Negative feedback on APT loop, I think it is; suppresses Leutenizing hormone, per female cycle.)

But with our cyclic approaches anyway, might be able to accomplish something. :-)

Your thoughts?
-Dianna

Hey there demonid P, what up B?. (j/k) Lmao

Ok I dig where you're going, and I've spent amount of time thinking about this lol, meaning the idea of boosting free T to benefit biosynthesis of E. Btw, Pharma E2 inhibits DHT (I don't know the exact amount as of yet, (I will though lol).

Negative feedback is a good example, in initial treatment phase some meds increase lutenizing hormone before it (med) stabilizes (30-45 days). To me, this says the science is there to manipulate meds.

Something I'm close to understanding is using our diurnal rhythms to promote growth stages that can boost feminization (similar to some animal based studies). And I think amino acids & peptides in combination with a few other things I'll mention later will trigger this boost.