26-01-2016, 09:26 PM
That's a great find Atom, (thanks)
It looks like 6 -O-galloylalbiflorin and pentagalloylglucose acts like flutamide (a strong non-steroidal anti-androgen), but flutamide carries hepatic risks (toxicity). Aside from the health benefits of WP, the fact it inhibits human prostate cancer cells is a major find.
So, in ovaries WP promotes aromatase, (I believe in the breasts too), inhibits DHT in sebum, inhibits prostate cancer cells, (which means it inhibits C17 @ CYP17 P450 enzyme, a strong anti-androgen. The lab dosage was 2 grams (I'll have to double check). Roots be king.
It looks like 6 -O-galloylalbiflorin and pentagalloylglucose acts like flutamide (a strong non-steroidal anti-androgen), but flutamide carries hepatic risks (toxicity). Aside from the health benefits of WP, the fact it inhibits human prostate cancer cells is a major find.
So, in ovaries WP promotes aromatase, (I believe in the breasts too), inhibits DHT in sebum, inhibits prostate cancer cells, (which means it inhibits C17 @ CYP17 P450 enzyme, a strong anti-androgen. The lab dosage was 2 grams (I'll have to double check). Roots be king.