09-01-2016, 06:40 AM
Btw, PM upregulates luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in both sexes, a direct feedback from the HPA (hypothalamus pituitary axis). And in women this is what extends their cycles (I call that generic birth control lol).
And........ PM also inhibits (partially) CYP 17 (blocks androgen synthesis) and induces CYP 19 aromatase (pro-breast growth action) some of you might know this action already though.
So, bottom line. If PM is authentic it will equal to about .5mg of E2, that's my opinion FWIW. The reason I say .5 (a rough calculation) is that deoxymiroestrol is 10x stronger than Miroestrol, as this is left out in previous valuations.
And........ PM also inhibits (partially) CYP 17 (blocks androgen synthesis) and induces CYP 19 aromatase (pro-breast growth action) some of you might know this action already though.
So, bottom line. If PM is authentic it will equal to about .5mg of E2, that's my opinion FWIW. The reason I say .5 (a rough calculation) is that deoxymiroestrol is 10x stronger than Miroestrol, as this is left out in previous valuations.