07-01-2016, 06:59 AM
dee-elle,
Hi there,
Lurking 3+ years, that's a long time, glad to hear from you...
, (thank you for the lovely comments)
The most current find was this:
The first pass metabolism destroys 80-85% of a product, so I try to opt for liquid or sublingual dosage. Although, here recently I think adding an oral combination with sublingual could be beneficial. A likely scenario (imo) 80% sublingual, 15% transdermal, and 5% oral (or something similar).
metabolism taking detours lol.
Hi there,
Lurking 3+ years, that's a long time, glad to hear from you...
, (thank you for the lovely comments) The most current find was this:
(31-12-2015, 11:36 PM)Lotus Wrote: Pure Light Chinese peony, helping oily skins to rebalance
http://www.naolys.com/media/pure_light_chinese_peony_en.pd
Quote: a significant inhibition of 5 alpha reductase is inhibited @ 23% compared with finasteride, that induces an inhibition of 38%.
Pure Light Chinese peony acts on different levels of epidermis before and after the phenomena of sebum surproduction by the sebaceous glands. First, it limits the quantity of the enzyme 5 alpha-reductase, which is at the origin of the activity of the hormon responsible for the production of sebum.
Paeonia lactiflora decreases testosterone production by inhibiting the conversion of delta 4-androstenedione to testosterone in the ovary, while stimulating aromatase activity in the ovary to promote estradiol synthesis.
The first pass metabolism destroys 80-85% of a product, so I try to opt for liquid or sublingual dosage. Although, here recently I think adding an oral combination with sublingual could be beneficial. A likely scenario (imo) 80% sublingual, 15% transdermal, and 5% oral (or something similar).
metabolism taking detours lol.