31-12-2015, 07:03 AM
(31-12-2015, 02:59 AM)Lotus Wrote:(31-12-2015, 02:40 AM)Lotus Wrote: By george I think I've figured it out,
By tricking a fat cell into thinking it's in a full (fed) state it eliminates the potential harmful side-effects such as obesity and cancer causing properties. Seen in this study:
Quote:The percentage conversion of androstenedione to estrone rises from 1-2% in normal weight subjects to 12- 15% in women who weigh 300-400 lb (135- 181 kg).
When fat cells are empty it's saying feed me. An example of this would be how high serum levels of natural estrogen tricks the brain into thinking its produced enough testosterone, which in turn slows the production of T down. In this example we trick your body into thinking its full, thereby the release of more fat from a "starved state" is inhibited.
A fed fat cell "in theory" (lol mine) produces an upregulated conversion of aromatase without being in this obese state.
Adipose tissue as a source of hormones
http://ajcn.nutrition.org/content/45/1/277.long
Ok, connecting the dots, from a previous post we see that this potential of how powerful FAT, really is, it's all around us (lol, literally).
How do we fulfill this need you ask?............answer: Leptin (again), insulin plays an important role in this too, no doubt.
(20-08-2015, 05:28 AM)Lotus Wrote: Eating high-fat foods may reduce free testosterone levels according to one study that measured serum levels of sex steroid hormones after ingestion of different types of food. High-protein and high-carbohydrate meals had no effect on serum hormone levels, but a fat-containing meal reduced free testosterone levels for 4 hours (Killinger et. al. 1987)....... (in men).
The resulting hormone imbalance (too much estrogen and not enough free testosterone) in obese men partially explains why so many are impotent and experience a wide range of premature degenerative diseases (Blum et al. 1988).
(20-08-2015, 05:04 AM)Lotus Wrote: Polyunsaturated fats and prostaglandins stimulate the expression of aromatase, the enzyme that synthesizes estrogen.
Generally, ingested fats show up in adipose tissue depots and in the bloodstream (in lipoproteins or as FFA) and the ultimate storage site is determined by the places where blood flows the greatest. Women, for instance, store a greater proportion of ingested fats in the subcutaneous adipose tissue depots than men because of these regional blood flow differences (Jensen, Sarr, Dumesic, Southorn, & Levine, 2003).
In principle, on activation by the lipolytic hormones, short, polyunsaturated fats (e.g., linoleate) would be mobilized in preference to longer, saturated fats because they are more accessible to the water-soluble enzyme, HSL, which catalyzes the release of fatty acids from glycerol. (To add another layer of complexity, depending on the circumstances, adipose tissue depots contribute differentially to the blood FFA pool [Mittendorfer, Liem, Patterson, Miles, & Klein, 2003]). Nonetheless, in reality, on average, plenty of saturated (e.g., stearate and palmitate) and monounsaturated fats (e.g., oleate and palmitoleate) are released in addition to polyunsaturated fats, so when fats are mobilized a mixture is available for use as fuel by tissues elsewhere (Staiger et al., 2004).
http://www.andrewkimblog.com/2013/02/dr-...fe-of.html
Soooo much reading but FOR TOMORROW ... It is New Year's Eve after all