30-04-2015, 03:59 AM
(30-04-2015, 03:32 AM)froger Wrote:(28-04-2015, 12:35 AM)Lotus Wrote: The death of DHT,
dutasteride (the strongest anti-androgen) dual inhibition reduces median serum DHT levels by 90% at 2 weeks and 93% at 2 years.
This is why breast growth takes a while, include feminaztion in the statement. So, a little help from the studio audience please.
If males produce 3mg to 10mg of Testosterone daily and 4% gets converted to DHT, how much anti-androgens are needed to give DHT a proper burial?,(I think of it as the NBE therapeutic edge)
????..... Give it your best shot, no one answer is a wrong answer.
Wouldn't it depend on the effectiveness of the particular anti-androgen(s) in each given individual? If John has a higher tolerance than Tim, then John would need more.
True froger it would, I suppose that's why the big variance. The other variable is the active part (free state) the concentration is. I'm looking at if the strongest AA out there (dutas) is eventually up to 93% after 2 years we're certainly leaving out of DHT on the table then we know about. In other words, most labs won't test for DHT or free T unless directed because of the expense (insurance). But let's say the most aggressive Hrt plan using dutas is 2mg, and let's throw in Finasteride For the heck of it, 6 mg in an aggressive hrt plan, which Finasteride gets reported @ DHT inhibition of 90 to 95%, but we'll say 90% for now. If we're at the top end (10 mg) were 4 mg shy of that therapeutic threshold to bury DHT. Dutas at 93% because of its strength (3% more) I'm gonna say 2mg shy. Sorry my math sucks, but 4% (DHT) of 10 mg of T is .4 mg but.....DHT is 30 times stronger than T, so we'll need 28mg more of Finasteride and 20-22mg of dutas. Did I loose yah?, I wouldn't be surprised lol.
So, no answer seems unreasonable to me, or better math skills.