14-04-2015, 03:01 AM
T. foenum-graecum (aka-Fenugreek)
Here's another related study concerning FG, MCF-7 is positive for ER-a, which FG clearly shows positive cell sensitivity and stimulates growth. And while I believe some phtyoestrogens down-regulate cell lines and receptors resulting in an anti-estrogenic and influence androgens, FG hasnt shown that specificity except in one study, which I noted.
Estrogen-like activities and cytotoxicity effects of Thai herbal medicines as natural ingredients in anti-ageing
With respect to herbal medicines traditionally used as a galactogogue to increase inadequate breast milk supply, only T. foenum-graecum promoted the growth of MCF-7 cells in a dose-dependent manner.
http://www.nanotec.or.th/en/wp-content/uploads/2012/09/64525.pdf
MCF-7 cells are useful for in vitro breast cancer studies because the cell line has retained several ideal characteristics particular to the mammary epithelium. These include the ability for MCF-7 cells to process estrogen, in the form of estradiol, via estrogen receptors in the cell cytoplasm. This makes the MCF-7 cell line an estrogen receptor (ER) positive control cell line.
http://www.mcf7.com
Here's another related study concerning FG, MCF-7 is positive for ER-a, which FG clearly shows positive cell sensitivity and stimulates growth. And while I believe some phtyoestrogens down-regulate cell lines and receptors resulting in an anti-estrogenic and influence androgens, FG hasnt shown that specificity except in one study, which I noted.
Estrogen-like activities and cytotoxicity effects of Thai herbal medicines as natural ingredients in anti-ageing
With respect to herbal medicines traditionally used as a galactogogue to increase inadequate breast milk supply, only T. foenum-graecum promoted the growth of MCF-7 cells in a dose-dependent manner.
http://www.nanotec.or.th/en/wp-content/uploads/2012/09/64525.pdf
MCF-7 cells are useful for in vitro breast cancer studies because the cell line has retained several ideal characteristics particular to the mammary epithelium. These include the ability for MCF-7 cells to process estrogen, in the form of estradiol, via estrogen receptors in the cell cytoplasm. This makes the MCF-7 cell line an estrogen receptor (ER) positive control cell line.
http://www.mcf7.com