[EvaMarie]

Eva,

Progesterone restores estrogen receptor sensitivity to its original state. Progesterone also protects against the proliferate side of breast cancer in estrogen receptors. It also down regulates DHT through 5 alpha reductase. It has no feminzing effect. Progesterone in the presence of estrogen up-regulates side branching, and estrogen promotes the elongation of breasts. But......an odd spin is that progesterone down regulates it's own receptor, crazy huh?.

Eva, I'm wondering if you took progesterone at night, (which progesterone also promotes restful sleep) and I mean daily. Only in a smaller dose....I'm just thinking to restore the fullness/projection issue. They way I see pharma E release and it's spikes throughout the day it would make sense to get that restorative phase from progesterone, plus....GH (growth hormone) is promoted by restful sleep. I dunno, it's what I would do.

But I'd also tell you need EFA's (essential fatty acids) to reduce the inflammatory response. And the body inner inflammatory markers effects everything from high blood pressure, diabetes, the release of hormones through blood proteinn....,and other bad stuff too.

Omega 3's is what I mean ....chia seeds are great.....krill oil too.

Yea I always take my P later in the evening but even 200mg is sometimes too much for me and it sometimes will make my skin crawl... Believe it or not sometimes I'll get a very uncomfortable not quite painful sensation in my hips that can really bug me... Maybe a growing pain but doubtful at 46 years old My hips have been filling out SLOWLY though so who knows

P is active all over not just the boobs, it has a nice calming effect on my mind as well and early in the cycle I feel like it increases my ability to concentrate and think... I can also have some pretty wild and very lucid dreams After a while though it seems to slow down boob growth sensations and I'll get more cranky and even bloated... Then I go off it and in a day or two I can really feel all that E and they get buzzing again I'll have more energy and feel a lot more emotional for a few days then even a bit restless and anxious.... Boobs seem to shrink a bit and calm down... Then I start the whole cycle over I have tried to just stay on 100mg all the time but I actually like the cycle better... Maybe it resets things, donno but I like it

For a while I just cut it down to 100mg and about mid cycle Id up it to 200mg for a while then go back down and then off of it...
This cycle Ive decided to try to go with 200mg from the start but starting today Im going with 100mg after lunch and I'll do another 100mg later tonight... Then after a week try upping it to 200mg before bed for 300mg total...

I doubt I have any smaller E spikes during the day, more like over a couple of days... I take EV shots every five days, they give a fast rise and then fall that takes about a 5 days and peaks near the middle... So Im always either going up or down on E and its never really steady with big peaks every five days... Lately since I still have a nice stash Ive added a Climera 100 matrix E patch in an attempt keep the lows a bit higher... Seems to help so far even though compared to the shots a single patch is pretty weak... Maybe even just mostly psychological but I feel a bit better and they are easy enough to just stick on and forget about in between shots

I donno about those supplements but I do like to try eat fish twice a week and a lot of salads with oil and vinegar based dressings

All I know is E and P work together but getting the right balance with endogenous hormones has to be nearly impossible... Its a bit of a controversy and its hard to find anything conclusive on P's role in MtF HRT or even cis for women that undergo surgical menopause... The big difference of course is that cis women are already fully feminized...