06-03-2015, 05:04 AM
(06-03-2015, 04:37 AM)iaboy Wrote: Quick, I am drowning. Throw me a rope, or a bone. It will go well with my head. (get it, bone head) hahaha, o.k., not funny. So what in Iowa does it all mean??? Eat corn, but not the silk??? WTF????I feel like I just stepped into advance Calculus 201 and flunked 9th grade math...
Ah snap!, ask me something easy huh.

You'd have to go back here first to make any sense at all. There's too many parts to wrap it up in a bow. (Sorry)
(05-03-2015, 05:02 PM)Lotus Wrote: The health benefits of phyto's are well documented (especially here). These intracellular pathways are very interesting to say the least. That fact that someone did these kinds of studies blows me away lol. The estrogen receptor bioavailability chart I listed on another thread ties into these two studies. Put them all together and you get the sense of a reality check of sorts on NBE. The takeaway is that this info explains why we have slow, or no growth at all for some. Plus, I would even go as far to say the same holds true for HRT, and that glaring fact was E2 wasn't strong at binding to ER-a (the growth receptor). Which explains why HRT is slow going too, which if I did HRT I'd add these things below, that's just my opinion though. Estradiol (E2) doesn't all get bound to the estrogen receptors. Consider this though, increased levels of phyto's block out the body's own "natural estrogens", I'd say that's something you can ill afford when trying to grow breasts.
I think the obvious choice is to balance herbs that are PRO-ER-a with ER-b (protective receptor). Turmeric, green tea, essential fatty acids, and certain phtyoestrogens. 5 ar inhibitors are still a viable choice, reishi binds to ER's, not sure which one yet. WP is still a good choice. New weapons are things like 17 beta HSD's, type 1 & 4, plus CYP19 is still a viable option considering the andro to estro pathway,(that backdoor pathway is yet to be tapped).
cAMP or "cyclic adenosine monophosphate" is another possible NBE tool. Imo cAMP ties into fatty acids/aromatase or in large part, cAMP delivers FA's to hormones. In other words increasing blood flow to the receptors increase their bioavailability. Forilskin comes to mind, but quite honestly I think fatty acids work quite the same way.
cAMP is a second messenger, used for intracellular signal transduction, such as transferring the effects of hormones like glucagon and adrenaline, which cannot get through the cell membrane. Its purposes include the activation of protein kinases and regulating the effects of adrenaline and glucagon. It is also used to regulate the passage of Ca2+ through ion channels.
cyclic adenosine monophosphate
http://psychology.wikia.com/wiki/Cyclic_...ophosphate