[GoneGirl]

Clara, how did the mix of E and PM go? , I thought I had read in another thread about weaker E blocking or locking the receptors so the stronger E would not be used, would this be the case here too ?? Or does E and PM co_exist just fine?

Hi Janet,

I do believe that PM (miroestrol) competes with estradiol for estrogen receptors in breast tissue. That's good for lowering the risk of breast cancer. But, the reason that I've added 1000 mg of PM back into my regimen was for other benefits of PM. I liked that PM was helping to ease morning joint stiffness which returned when I went off PM. On the other hand, my nipples become 'hard' and my areolas dark on the PM, which my DW is not particularly crazy about, and they do tend to show extremely well through a single layer of clothing . I'm exploring the possibility of finding another herb that helps with joint health so that I can drop the PM. I'm not that concerned about breast cancer because there are no instances of it in my family background. I also don't like the fact that the phyto-estrogen from PM doesn't show up in the standard estrogen tests that my endo will be calling for to help establish an optimal sex hormone balance.

Don't take these comments as a shift in my attitude about the benefits of herbal HRT. I do NOT regret having used herbs the first 7 months of my feminization program. I needed that time to really come to know myself better, and to grow into my true gender identity. I highly recommend herbal HRT for those who are in the exploratory phase of their gender conundrum.

Hugs,

Clara